UniProt O00541
Pescadillo homolog (O00541)
Pescadillo homolog (UniProt O00541): 27 experimental structures and 1 predicted model on GenesisL1, 70 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- O00541
- Protein
- Pescadillo homolog
- Experimental structures
- 27
- Predicted models
- 1
- Pockets
- 70 · 26 records with a druggable one
Structures
28 records of O00541 in the MolNFT archive: 27 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2EP8 | Solution structure of the BRCT domain from human Pescadillo homolog 1 | solution nmr | A | — | — |
| 2EP8 | Solution structure of the brct domain from human pescadillo homolog 1 | solution nmr | A | — | — |
| 8FKP | Human nucleolar pre-60S ribosomal subunit (State A1) | electron microscopy | SM | — | 2 (best 0.86) |
| 8FKQ | Human nucleolar pre-60S ribosomal subunit (State A2) | electron microscopy | SM | — | 3 (best 0.91) |
| 8FKR | Human nucleolar pre-60S ribosomal subunit (State B1) | electron microscopy | SM | — | 3 (best 0.90) |
| 8FKS | Human nucleolar pre-60S ribosomal subunit (State B2) | electron microscopy | SM | — | 3 (best 0.87) |
| 8FKT | Human nucleolar pre-60S ribosomal subunit (State C1) | electron microscopy | SM | — | 2 (best 0.91) |
| 8FKU | Human nucleolar pre-60S ribosomal subunit (State C2) | electron microscopy | SM | — | 1 (best 0.86) |
| 8FKV | Human nucleolar pre-60S ribosomal subunit (State D1) | electron microscopy | SM | — | 1 (best 0.86) |
| 8FKW | Human nucleolar pre-60S ribosomal subunit (State D2) | electron microscopy | SM | — | 1 (best 0.86) |
| 8FKX | Human nucleolar pre-60S ribosomal subunit (State E) | electron microscopy | SM | — | 1 (best 0.86) |
| 8FKY | Human nucleolar pre-60S ribosomal subunit (State F) | electron microscopy | SM | — | 3 (best 0.87) |
| 8FKZ | Human nucleolar pre-60S ribosomal subunit (State G) | electron microscopy | SM | — | 2 (best 0.87) |
| 8FL2 | Human nuclear pre-60S ribosomal subunit (State I1) | electron microscopy | SM | — | 3 (best 0.88) |
| 8FL3 | Human nuclear pre-60S ribosomal subunit (State I2) | electron microscopy | SM | — | 4 (best 0.88) |
| 8FL4 | Human nuclear pre-60S ribosomal subunit (State I3) | electron microscopy | SM | — | 2 (best 0.89) |
| 8FL6 | Human nuclear pre-60S ribosomal subunit (State J1) | electron microscopy | SM | — | 3 (best 0.88) |
| 8FL7 | Human nuclear pre-60S ribosomal subunit (State J2) | electron microscopy | SM | — | 3 (best 0.88) |
| 8FLA | Human nuclear pre-60S ribosomal subunit (State K1) | electron microscopy | SM | — | 3 (best 0.88) |
| 8FLB | Human nuclear pre-60S ribosomal subunit (State K2) | electron microscopy | SM | — | 3 (best 0.89) |
| 8FLD | Human nuclear pre-60S ribosomal subunit (State L1) | electron microscopy | SM | — | 3 (best 0.88) |
| 8FLE | Human nuclear pre-60S ribosomal subunit (State L2) | electron microscopy | SM | — | 3 (best 0.89) |
| 8INE | human nuclear pre-60S ribosomal particle - State G' | electron microscopy | v | — | 3 (best 0.88) |
| 8INF | human nuclear pre-60S ribosomal particle - State F' | electron microscopy | v | — | 2 (best 0.88) |
| 8IPX | human nuclear pre-60S ribosomal particle - State C' | electron microscopy | q | — | 4 (best 0.89) |
| 8IPY | human nuclear pre-60S ribosomal particle - State D' | electron microscopy | q | — | 4 (best 0.89) |
| 8IR3 | human nuclear pre-60S ribosomal particle - State B' | electron microscopy | q | — | 3 (best 0.87) |
| O00541 | AlphaFold monomer V2.0 prediction for pescadillo homolog (O00541) | predicted | A | — | 5 (best 0.67) |
Experiment against prediction
- 8INE chain v against the predicted model O00541: TM-score 0.97, RMSD 1.19 Å
- 8IPX chain q against the predicted model O00541: TM-score 0.97, RMSD 1.21 Å
- 8IPY chain q against the predicted model O00541: TM-score 0.97, RMSD 1.21 Å
- 8IR3 chain q against the predicted model O00541: TM-score 0.97, RMSD 1.22 Å
- 8INF chain v against the predicted model O00541: TM-score 0.97, RMSD 1.22 Å
- 8FL4 chain SM against the predicted model O00541: TM-score 0.97, RMSD 1.18 Å
- 8FKZ chain SM against the predicted model O00541: TM-score 0.97, RMSD 1.28 Å
- 8FLD chain SM against the predicted model O00541: TM-score 0.97, RMSD 1.27 Å
- 8FL7 chain SM against the predicted model O00541: TM-score 0.97, RMSD 1.28 Å
- 8FLA chain SM against the predicted model O00541: TM-score 0.97, RMSD 1.28 Å
Elsewhere
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