UniProt O00488
Zinc finger protein 593 (O00488)
Zinc finger protein 593 (UniProt O00488): 26 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 54 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- O00488
- Protein
- Zinc finger protein 593
- Experimental structures
- 26
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 54 · 24 records with a druggable one
Structures
27 records of O00488 in the MolNFT archive: 26 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1ZR9 | Solution Structure of a Human C2H2-type Zinc Finger Protein | solution nmr | A | ZN | — |
| 1ZR9 | Solution structure of a human C2H2-type zinc finger protein | solution nmr | A | ZN | — |
| 6LSS | Cryo-EM structure of a pre-60S ribosomal subunit - state preA | electron microscopy | 9 | MG | 1 (best 0.86) |
| 6LU8 | Cryo-EM structure of a human pre-60S ribosomal subunit - state A | electron microscopy | 9 | MG | 2 (best 0.87) |
| 8FL2 | Human nuclear pre-60S ribosomal subunit (State I1) | electron microscopy | NP | ZN | 2 (best 0.86) |
| 8FL3 | Human nuclear pre-60S ribosomal subunit (State I2) | electron microscopy | NP | MG, ZN | 3 (best 0.88) |
| 8FL4 | Human nuclear pre-60S ribosomal subunit (State I3) | electron microscopy | NP | ZN | 2 (best 0.88) |
| 8FL6 | Human nuclear pre-60S ribosomal subunit (State J1) | electron microscopy | NP | ZN | 4 (best 0.88) |
| 8FL7 | Human nuclear pre-60S ribosomal subunit (State J2) | electron microscopy | NP | MG, ZN | 4 (best 0.89) |
| 8FL9 | Human nuclear pre-60S ribosomal subunit (State J3) | electron microscopy | NP | MG, ZN | 2 (best 0.88) |
| 8FLA | Human nuclear pre-60S ribosomal subunit (State K1) | electron microscopy | NP | ZN | 2 (best 0.88) |
| 8FLB | Human nuclear pre-60S ribosomal subunit (State K2) | electron microscopy | NP | ZN | 3 (best 0.88) |
| 8FLC | Human nuclear pre-60S ribosomal subunit (State K3) | electron microscopy | NP | MG, ZN | 4 (best 0.88) |
| 8FLD | Human nuclear pre-60S ribosomal subunit (State L1) | electron microscopy | NP | ZN | 1 (best 0.89) |
| 8FLE | Human nuclear pre-60S ribosomal subunit (State L2) | electron microscopy | NP | ZN | 3 (best 0.89) |
| 8FLF | Human nuclear pre-60S ribosomal subunit (State L3) | electron microscopy | NP | ZN | 2 (best 0.88) |
| 8IDT | human nuclear pre-60S ribosomal particle - State G | electron microscopy | 9 | — | 4 (best 0.88) |
| 8IDY | human nuclear pre-60S ribosomal particle - State F | electron microscopy | 9 | — | 2 (best 0.88) |
| 8IE3 | human nuclear pre-60S ribosomal particle - State E | electron microscopy | 9 | — | 2 (best 0.89) |
| 8INE | human nuclear pre-60S ribosomal particle - State G' | electron microscopy | 9 | — | 2 (best 0.89) |
| 8INF | human nuclear pre-60S ribosomal particle - State F' | electron microscopy | 9 | — | 2 (best 0.89) |
| 8INK | human nuclear pre-60S ribosomal particle - State D | electron microscopy | 9 | — | 1 (best 0.87) |
| 8IPD | human nuclear pre-60S ribosomal particle - State C | electron microscopy | 9 | — | 1 (best 0.87) |
| 8IPX | human nuclear pre-60S ribosomal particle - State C' | electron microscopy | 9 | — | 1 (best 0.89) |
| 8IPY | human nuclear pre-60S ribosomal particle - State D' | electron microscopy | 9 | — | 1 (best 0.89) |
| 8IR3 | human nuclear pre-60S ribosomal particle - State B' | electron microscopy | 9 | — | 2 (best 0.87) |
| O00488 | AlphaFold monomer V2.0 prediction for zinc finger protein 593 (O00488) | predicted | A | — | 1 (best 0.40) |
Ligands
Experiment against prediction
- 8FLA chain NP against the predicted model O00488: TM-score 0.79, RMSD 1.81 Å
- 8FL7 chain NP against the predicted model O00488: TM-score 0.78, RMSD 1.83 Å
- 8FLB chain NP against the predicted model O00488: TM-score 0.78, RMSD 1.83 Å
- 8FLC chain NP against the predicted model O00488: TM-score 0.78, RMSD 1.84 Å
- 8FL9 chain NP against the predicted model O00488: TM-score 0.78, RMSD 1.86 Å
- 8FLF chain NP against the predicted model O00488: TM-score 0.78, RMSD 1.91 Å
- 8FLE chain NP against the predicted model O00488: TM-score 0.78, RMSD 1.92 Å
- 8FL6 chain NP against the predicted model O00488: TM-score 0.78, RMSD 1.87 Å
- 8FLD chain NP against the predicted model O00488: TM-score 0.78, RMSD 1.93 Å
- 8FL4 chain NP against the predicted model O00488: TM-score 0.78, RMSD 1.86 Å
Elsewhere
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