UniProt O00311
Cell division cycle 7-related protein kinase,Cell division cycle 7-related protein kinase,Cell division cycle 7-related protein kinase (O00311)
Cell division cycle 7-related protein kinase,Cell division cycle 7-related protein kinase,Cell division cycle 7-related protein kinase (UniProt O00311), EC 2.7.11.1: 13 experimental structures and 1 predicted model on GenesisL1…
- UniProt
- O00311
- Protein
- Cell division cycle 7-related protein kinase,Cell division cycle 7-related…
- EC
- 2.7.11.1
- Experimental structures
- 13
- Predicted models
- 1
- Ligands
- 7
- Pockets
- 4 · 1 record with a druggable one
Structures
14 records of O00311 in the MolNFT archive: 13 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4F99 | Human CDC7 kinase in complex with DBF4 and nucleotide | x-ray diffraction | A | — | — |
| 4F99 | Human CDC7 kinase in complex with DBF4 and nucleotide | x-ray diffraction | A | — | — |
| 4F9A | Human CDC7 kinase in complex with DBF4 and nucleotide | x-ray diffraction | A, C | — | — |
| 4F9A | Human CDC7 kinase in complex with DBF4 and nucleotide | x-ray diffraction | A, C | — | — |
| 4F9B | Human CDC7 kinase in complex with DBF4 and PHA767491 | x-ray diffraction | A, C | — | — |
| 4F9B | Human CDC7 kinase in complex with DBF4 and PHA767491 | x-ray diffraction | A, C | — | — |
| 4F9C | Human CDC7 kinase in complex with DBF4 and XL413 | x-ray diffraction | A | — | — |
| 4F9C | Human CDC7 kinase in complex with DBF4 and XL413 | x-ray diffraction | A | — | — |
| 5UWR | Crystal structure of CDC7 nes peptide (extended) in complex with CRM1- ran-RANBP1 | x-ray diffraction | D | — | — |
| 6YA6 | Minimal construct of CDC7-DBF4 bound to XL413 | x-ray diffraction | A | 0SX, ZN, BO3, CL | — |
| 6YA7 | Cdc7-Dbf4 bound to an Mcm2-S40 derived bivalent substrate | x-ray diffraction | A | ZN, ADP | 4 (best 0.68) |
| 6YA7 | CDC7-DBF4 bound to an MCM2-S40 derived bivalent substrate | x-ray diffraction | A | ZN, ADP | — |
| 6YA8 | CDC7-DBF4 bound to ADP-BEF3 | x-ray diffraction | A | ADP, MG, BEF, ZN | — |
| O00311 | AlphaFold monomer V2.0 prediction for cell division cycle 7-related protein kinase (O00311) | predicted | A | — | — |
Ligands
- ZN · Zinc ion · in 4 records
- ADP · Adenosine-5'-diphosphate · in 3 records
- 0SX · 8-chloro-2-[(2S)-pyrrolidin-2-yl][1]benzofuro[3,2-d]pyrimidin-4(3H)-one · in 1 record
- BEF · Beryllium trifluoride ion · in 1 record
- BO3 · Boric acid · in 1 record
- CL · Chloride ion · in 1 record
- MG · Magnesium ion · in 1 record
Experiment against prediction
- 4F9C chain A against the predicted model O00311: TM-score 0.99, RMSD 0.64 Å
- 4F9C chain A against the predicted model O00311: TM-score 0.99, RMSD 0.64 Å
- 6YA6 chain A against the predicted model O00311: TM-score 0.99, RMSD 0.75 Å
- 4F9B chain C against the predicted model O00311: TM-score 0.99, RMSD 0.88 Å
- 4F9B chain C against the predicted model O00311: TM-score 0.99, RMSD 0.88 Å
- 6YA8 chain A against the predicted model O00311: TM-score 0.99, RMSD 0.86 Å
- 4F99 chain A against the predicted model O00311: TM-score 0.99, RMSD 1.01 Å
- 4F99 chain A against the predicted model O00311: TM-score 0.99, RMSD 1.01 Å
- 6YA7 chain A against the predicted model O00311: TM-score 0.98, RMSD 1.14 Å
- 6YA7 chain A against the predicted model O00311: TM-score 0.98, RMSD 1.14 Å
Elsewhere
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