UniProt O00294
Tubby-related protein 1 (O00294)
Tubby-related protein 1 (UniProt O00294): 4 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 37 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- O00294
- Protein
- Tubby-related protein 1
- Experimental structures
- 4
- Predicted models
- 1
- Ligands
- 3
- Pockets
- 37 · 5 records with a druggable one
Structures
5 records of O00294 in the MolNFT archive: 4 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2FIM | Structure of the C-terminal domain of Human Tubby-like protein 1 | x-ray diffraction | A, B | 3DP, SO4 | 6 (best 0.74) |
| 2FIM | Structure of the C-terminal domain of human tubby-like protein 1 | x-ray diffraction | A, B | 3DP, SO4 | 6 (best 0.74) |
| 3C5N | Structure of human TULP1 in complex with IP3 | x-ray diffraction | A, B | I3P | 8 (best 0.74) |
| 3C5N | Structure of human TULP1 in complex with IP3 | x-ray diffraction | A, B | I3P | 8 (best 0.74) |
| O00294 | AlphaFold monomer V2.0 prediction for tubby-related protein 1 (O00294) | predicted | A | — | 9 (best 0.77) |
Ligands
Experiment against prediction
- 2FIM chain A against the predicted model O00294: TM-score 0.98, RMSD 0.74 Å
- 2FIM chain A against the predicted model O00294: TM-score 0.98, RMSD 0.74 Å
- 3C5N chain A against the predicted model O00294: TM-score 0.98, RMSD 1.17 Å
- 3C5N chain A against the predicted model O00294: TM-score 0.98, RMSD 1.17 Å
- 3C5N chain B against the predicted model O00294: TM-score 0.96, RMSD 1.38 Å
- 3C5N chain B against the predicted model O00294: TM-score 0.96, RMSD 1.38 Å
- 2FIM chain B against the predicted model O00294: TM-score 0.95, RMSD 1.51 Å
- 2FIM chain B against the predicted model O00294: TM-score 0.95, RMSD 1.51 Å
Elsewhere
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