UniProt O00230
Cortistatin (O00230)
Cortistatin (UniProt O00230): 4 experimental structures and 1 predicted model on GenesisL1, 2 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- O00230
- Protein
- Cortistatin
- Experimental structures
- 4
- Predicted models
- 1
- Pockets
- 2 · 1 record with a druggable one
Structures
5 records of O00230 in the MolNFT archive: 4 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 7VDL | Cryo-EM structure of pseudoallergen receptor MRGPRX2 complex with circular cortistatin-14 | electron microscopy | L | — | 1 (best 0.69) |
| 7VDL | Cryo-EM structure of pseudoallergen receptor MRGPRX2 complex with circular cortistatin-14 | electron microscopy | L | — | — |
| 7VV4 | Cryo-EM structure of pseudoallergen receptor MRGPRX2 complex with linear cortistatin-14, local | electron microscopy | L | — | — |
| 8X8L | Cryo-EM structure of the cortistatin 17-bound Somatostatin receptor 5-Gi protein complex | electron microscopy | C | — | 1 (best 0.37) |
| O00230 | AlphaFold monomer V2.0 prediction for cortistatin (O00230) | predicted | A | — | — |
Experiment against prediction
- 7VDL chain L against the predicted model O00230: TM-score 0.66, RMSD 0.24 Å
- 7VDL chain L against the predicted model O00230: TM-score 0.66, RMSD 0.24 Å
- 7VV4 chain L against the predicted model O00230: TM-score 0.57, RMSD 1.37 Å
- 8X8L chain C against the predicted model O00230: TM-score 0.22, RMSD 1.66 Å
Elsewhere
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