UniProt O00203
AP-3 complex subunit beta-1 (O00203)
AP-3 complex subunit beta-1 (UniProt O00203): 5 experimental structures and 1 predicted model on GenesisL1, 67 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- O00203
- Protein
- AP-3 complex subunit beta-1
- Experimental structures
- 5
- Predicted models
- 1
- Pockets
- 67 · 5 records with a druggable one
Structures
6 records of O00203 in the MolNFT archive: 5 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 9C58 | AP-3 bound to myristoylated Arf1 (Q71L) | electron microscopy | B | — | 9 (best 0.83) |
| 9C59 | Human AP-3 dimer bound to myristoylated Arf1 (Q71L) and LAMP1 cargo on a lipid nanodisc | electron microscopy | B, b | — | 15 (best 0.79) |
| 9C5A | AP-3 Arf1 dimeric interface, focused refinement | electron microscopy | B, b | — | 18 (best 0.80) |
| 9C5B | AP-3 bound to myristoylated Arf1 (Q71L) and LAMPI on a lipid nanodisc; combined map | electron microscopy | B | — | 13 (best 0.82) |
| 9C5C | Structure of Human Adaptor Protein Complex AP-3 in the Apo State | electron microscopy | B | — | 12 (best 0.72) |
| O00203 | AlphaFold monomer V2.0 prediction for ap-3 complex subunit beta-1 (O00203) | predicted | A | — | — |
Experiment against prediction
- 9C5A chain b against the predicted model O00203: TM-score 0.93, RMSD 2.20 Å
- 9C5A chain B against the predicted model O00203: TM-score 0.93, RMSD 2.20 Å
- 9C5B chain B against the predicted model O00203: TM-score 0.92, RMSD 2.52 Å
- 9C59 chain B against the predicted model O00203: TM-score 0.92, RMSD 2.56 Å
- 9C59 chain b against the predicted model O00203: TM-score 0.92, RMSD 2.56 Å
- 9C5C chain B against the predicted model O00203: TM-score 0.89, RMSD 2.73 Å
- 9C58 chain B against the predicted model O00203: TM-score 0.88, RMSD 2.88 Å
Elsewhere
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