UniProt M9TLW3
RNA-directed RNA polymerase catalytic subunit (M9TLW3)
RNA-directed RNA polymerase catalytic subunit (UniProt M9TLW3), EC 2.7.7.48: 5 experimental structures on GenesisL1, 1 ligand bound, 91 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- M9TLW3
- Protein
- RNA-directed RNA polymerase catalytic subunit
- EC
- 2.7.7.48
- Experimental structures
- 5
- Predicted models
- 0
- Ligands
- 1
- Pockets
- 91 · 5 records with a druggable one
Structures
5 records of M9TLW3 in the MolNFT archive: 5 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6TU5 | Influenza A/H7N9 polymerase core (apo) | x-ray diffraction | BBB, EEE | MG | 20 (best 0.84) |
| 7R0E | Early transcription elongation state of influenza A/H7N9 polymerase backtracked due to double… | electron microscopy | B | MG | 16 (best 0.89) |
| 7ZPL | Symmetric dimer of influenza A/H7N9 polymerase bound to 5' vRNA hook | electron microscopy | B, E | MG | 19 (best 0.85) |
| 8PM0 | Influenza A/H7N9 polymerase in replicase-like conformation in pre-initiation state with Pol II pS5… | electron microscopy | B | MG | 16 (best 0.85) |
| 8POH | Influenza A/H7N9 polymerase symmetric dimer bound to the promoter (PA K289A/C489R) | electron microscopy | B, F | MG | 20 (best 0.83) |
Ligands
- MG · Magnesium ion · in 5 records
Elsewhere
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