UniProt M9TI86
Polymerase acidic protein (M9TI86)
Polymerase acidic protein (UniProt M9TI86), EC 3.1.-.-: 12 experimental structures on GenesisL1, 1 ligand bound, 177 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- M9TI86
- Protein
- Polymerase acidic protein
- EC
- 3.1.-.-
- Experimental structures
- 12
- Predicted models
- 0
- Ligands
- 1
- Pockets
- 177 · 12 records with a druggable one
Structures
12 records of M9TI86 in the MolNFT archive: 12 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6TU5 | Influenza A/H7N9 polymerase core (apo) | x-ray diffraction | AAA, DDD | — | 16 (best 0.84) |
| 7R0E | Early transcription elongation state of influenza A/H7N9 polymerase backtracked due to double… | electron microscopy | A | MG | 14 (best 0.89) |
| 7Z4O | Influenza A/H7N9 polymerase core dimer with Pol II pSer5 CTD peptide mimic bound in site 2A | x-ray diffraction | AAA, DDD | — | 19 (best 0.77) |
| 7ZPL | Symmetric dimer of influenza A/H7N9 polymerase bound to 5' vRNA hook | electron microscopy | A, D | — | 18 (best 0.85) |
| 8PM0 | Influenza A/H7N9 polymerase in replicase-like conformation in pre-initiation state with Pol II pS5… | electron microscopy | A | — | 11 (best 0.85) |
| 8PNQ | Influenza A/H7N9 polymerase in elongation state with continuous Pol II pS5 CTD peptide mimic bound… | electron microscopy | A | — | 14 (best 0.89) |
| 8POH | Influenza A/H7N9 polymerase symmetric dimer bound to the promoter (PA K289A/C489R) | electron microscopy | A, E | — | 18 (best 0.83) |
| 8R3K | Influenza A/H7N9 polymerase in self-stalled pre-termination state, with Pol II pS5 CTD peptide… | electron microscopy | A | — | 15 (best 0.90) |
| 8R3L | Influenza A/H7N9 polymerase in pre-initiation state, intermediate conformation (I) with PB2-C(I)… | electron microscopy | A | — | 14 (best 0.85) |
| 8RMR | Influenza polymerase A/H7N9-4M replication complex, an asymmetric polymerase dimer bound to human… | electron microscopy | A, D | — | 13 (best 0.83) |
| 8RMS | Influenza polymerase A/H7N9-4M replicase minus 627(R) (from "Influenza polymerase A/H7N9-4M… | electron microscopy | A | — | 10 (best 0.85) |
| 8RN0 | Influenza polymerase A/H7N9-4M encapsidase plus 627(R) / human ANP32A (from "Influenza polymerase… | electron microscopy | D | — | 15 (best 0.81) |
Ligands
- MG · Magnesium ion · in 1 record
Elsewhere
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