UniProt M9TGV3
Enoyl-acyl carrier protein reductase (M9TGV3)
Enoyl-acyl carrier protein reductase (UniProt M9TGV3), EC 1.3.1.9: 18 experimental structures on GenesisL1, 5 ligands bound, 23 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- M9TGV3
- Protein
- Enoyl-acyl carrier protein reductase
- EC
- 1.3.1.9
- Experimental structures
- 18
- Predicted models
- 0
- Ligands
- 5
- Pockets
- 23 · 2 records with a druggable one
Structures
18 records of M9TGV3 in the MolNFT archive: 18 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4TRO | Structure of the enoyl-ACP reductase of Mycobacterium tuberculosis InhA, inhibited with the active… | x-ray diffraction | A | — | — |
| 4TRO | Structure of the enoyl-acp reductase of mycobacterium tuberculosis inha, inhibited with the active… | x-ray diffraction | A | — | — |
| 4UVD | Discovery of pyrimidine isoxazoles InhA in complex with compound 6 | x-ray diffraction | A | — | — |
| 4UVD | Discovery of pyrimidine isoxazoles inha in complex with compound 6 | x-ray diffraction | A | — | — |
| 4UVE | Discovery of pyrimidine isoxazoles InhA in complex with compound 9 | x-ray diffraction | A | — | — |
| 4UVE | Discovery of pyrimidine isoxazoles inha in complex with compound 9 | x-ray diffraction | A | — | — |
| 4UVG | Discovery of pyrimidine isoxazoles InhA in complex with compound 15 | x-ray diffraction | A | — | — |
| 4UVG | Discovery of pyrimidine isoxazoles inha in complex with compound 15 | x-ray diffraction | A | — | — |
| 4UVH | Discovery of pyrimidine isoxazoles InhA in complex with compound 10 | x-ray diffraction | A, B, C, D | — | — |
| 4UVH | Discovery of pyrimidine isoxazoles inha in complex with compound 10 | x-ray diffraction | A, B, C, D | — | — |
| 4UVI | Discovery of pyrimidine isoxazoles InhA in complex with compound 23 | x-ray diffraction | A, B, C, D | — | — |
| 4UVI | Discovery of pyrimidine isoxazoles inha in complex with compound 23 | x-ray diffraction | A, B, C, D | — | — |
| 5COQ | The effect of valine to alanine mutation on InhA enzyme crystallization pattern and substrate… | x-ray diffraction | A, B, C, D | NAD, TCU, NA | 10 (best 0.83) |
| 5COQ | The effect of valine to alanine mutation on inha enzyme crystallization pattern and substrate… | x-ray diffraction | A, B, C, D | — | — |
| 5CP8 | The effect of isoleucine to alanine mutation on inha enzyme crystallization pattern and substrate… | x-ray diffraction | A | — | — |
| 5CPB | The effect of isoleucine to alanine mutation on inha enzyme crystallization pattern and inhibition… | x-ray diffraction | A, B, C, D, E, F | — | — |
| 5G0W | InhA in complex with a DNA encoded library hit | x-ray diffraction | A, B, C, D | NAD, MG, 9NU | 13 (best 0.83) |
| 5G0W | Inha in complex with a DNA encoded library hit | x-ray diffraction | A, B, C, D | — | — |
Ligands
- NAD · Nicotinamide-adenine-dinucleotide · in 2 records
- 9NU · (2S,4S)-N-methyl-4-[[(2S,3R)-3-[(2-methylpropan-2-yl)oxy]-2-[[4-(pyrazol-1-ylmethyl)phenyl]carbonylamino]butanoyl]amino]-1-(phenylcarbonyl)pyrrolidine-2-carboxamide · in 1 record
- MG · Magnesium ion · in 1 record
- NA · Sodium ion · in 1 record
- TCU · 5-hexyl-2-(2-methylphenoxy)phenol · in 1 record
Elsewhere
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