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UniProt M1FYE4

Sterol 14alpha-demethylase (M1FYE4)

Sterol 14alpha-demethylase (UniProt M1FYE4), EC 1.14.13.70: 2 experimental structures on GenesisL1, 2 ligands bound, 20 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.

UniProt
M1FYE4
Protein
Sterol 14alpha-demethylase
EC
1.14.13.70
Experimental structures
2
Predicted models
0
Ligands
2
Pockets
20 · 1 record with a druggable one

Structures

2 records of M1FYE4 in the MolNFT archive: 2 experimental, 0 predicted.

EntryTitleMethodChainsLigandsPockets
6FMOCrystal structure of the substrate (obtusifoliol)-bound and ligand-free I105F mutant of sterol…x-ray diffractionA, B, C, DHEM, DVE20 (best 0.87)
6FMOCrystal structure of the substrate (obtusifoliol)-bound and ligand- free I105F mutant of sterol…x-ray diffractionA, B, C, DHEM, DVE—

Ligands

  • DVE · Obtusifoliol · in 2 records
  • HEM · Protoporphyrin IX containing Fe · in 2 records

Elsewhere

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