UniProt J3QSS1
Solute carrier family 12 member 3 (J3QSS1)
Solute carrier family 12 member 3 (UniProt J3QSS1): 3 experimental structures on GenesisL1, 4 ligands bound, 60 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- J3QSS1
- Protein
- Solute carrier family 12 member 3
- Experimental structures
- 3
- Predicted models
- 0
- Ligands
- 4
- Pockets
- 60 · 3 records with a druggable one
Structures
3 records of J3QSS1 in the MolNFT archive: 3 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 8VPN | Phosphorylated human NCC in complex with indapamide | electron microscopy | A, B | BL1, ATP | 20 (best 0.79) |
| 8VPP | Phosphorylated human NCC in complex with chlorthalidone | electron microscopy | A, B | KLT | 20 (best 0.78) |
| 9BWT | human sodium chloride cotransporter NCC S344E in the phosphorylation state and in complex with… | electron microscopy | A, B | ATP, HCZ | 20 (best 0.77) |
Ligands
- ATP · Adenosine-5'-triphosphate · in 2 records
- BL1 · 4-chloro-N-[(2S)-2-methyl-2,3-dihydro-1H-indol-1-yl]-3-sulfamoylbenzamide · in 1 record
- HCZ · 6-chloro-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide · in 1 record
- KLT · 2-chloro-5-[(1S)-1-hydroxy-3-oxo-2H-isoindol-1-yl]benzenesulfonamide · in 1 record
Elsewhere
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