UniProt J2LW81

Efflux pump membrane transporter (J2LW81)

Efflux pump membrane transporter (UniProt J2LW81): 2 experimental structures on GenesisL1, 3 ligands bound, 40 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.

UniProt: J2LW81
Protein: Efflux pump membrane transporter
Experimental structures: 2
Predicted models: 0
Ligands: 3
Pockets: 40 · 2 records with a druggable one

Structures

2 records of J2LW81 in the MolNFT archive: 2 experimental, 0 predicted.

Entry	Title	Method	Chains	Ligands	Pockets
8P1I	Single particle cryo-EM co-structure of Klebsiella pneumoniae AcrB with the BDM91288 efflux pump…	electron microscopy	A, B, C	WQW, WR6, PG8	20 (best 0.89)
8QZL	Single particle cryo-EM co-structure of Klebsiella pneumoniae AcrB with the BDM91288 efflux pump…	electron microscopy	A, B, C	WQW	20 (best 0.88)

Ligands

WQW · 3-chloranyl-2,6-di(piperazin-4-ium-1-yl)quinoline · in 2 records
PG8 · 1,2-dioctanoyl-sn-glycero-3-[phospho-rac-(1-glycerol) · in 1 record
WR6 · [(2~{R})-1-[[(2~{R})-2,3-bis(oxidanyl)propoxy]-oxidanyl-phosphoryl]oxy-3-undecanoyloxy-propan-2-yl] tricosanoate · in 1 record

Elsewhere

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