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UniProt I7BFC3

Protease (I7BFC3)

Protease (UniProt I7BFC3): 8 experimental structures on GenesisL1, 3 ligands bound, 1 pocket. Binding sites, pockets, druggability and 3D structures in GL1X.

UniProt
I7BFC3
Protein
Protease
Experimental structures
8
Predicted models
0
Ligands
3
Pockets
1 · 0 records with a druggable one

Structures

8 records of I7BFC3 in the MolNFT archive: 8 experimental, 0 predicted.

EntryTitleMethodChainsLigandsPockets
5T2ECrystal Structure of multi-drug resistant HIV-1 protease PR-S17x-ray diffractionACL1 (best 0.48)
5T2ECrystal structure of multi-drug resistant HIV-1 protease pr-S17x-ray diffractionACL—
5T2ZCrystal structure of multi-drug resistant HIV-1 protease pr-S17 in complex with darunavirx-ray diffractionA, B017—
6O54Crystal Structure of multi-drug resistant HIV-1 protease PR-S17 (D25N)x-ray diffractionXCL—
6O54Crystal structure of multi-drug resistant HIV-1 protease pr-S17 (D25N)x-ray diffractionXCL—
6O57Crystal structure of multi-drug resistant HIV-1 protease pr-S17 with a substrate analog P2-nc in P41x-ray diffractionA, B——
6O5ACrystal structure of multi-drug resistant HIV-1 protease pr-S17 with a substrate analog P2-nc in P61x-ray diffractionA, B——
6O5XCrystal structure of multi-drug resistant HIV-1 protease pr-S17 with substrate analog ca-P2x-ray diffractionA, B, C, DCL, NA—

Ligands

  • CL · Chloride ion · in 5 records
  • 017 · (3r,3as,6ar)-hexahydrofuro[2,3-b]furan-3-yl(1s,2r)-3-[[(4-aminophenyl)sulfonyl](isobutyl)amino]-1-benzyl-2-hydroxypropylcarbamate · in 1 record
  • NA · Sodium ion · in 1 record

Elsewhere

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