UniProt H7C794
DNA topoisomerase 4 subunit B (H7C794)
DNA topoisomerase 4 subunit B (UniProt H7C794): 2 experimental structures and 1 predicted model on GenesisL1, 5 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- H7C794
- Protein
- DNA topoisomerase 4 subunit B
- Experimental structures
- 2
- Predicted models
- 1
- Pockets
- 5 · 1 record with a druggable one
Structures
3 records of H7C794 in the MolNFT archive: 2 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4HZ5 | Pyrrolopyrimidine inhibitors of dna gyrase b and topoisomerase iv, part i: structure guided… | x-ray diffraction | A, B, C, D, E, F, G, H, J | — | — |
| 4HZ5 | Pyrrolopyrimidine inhibitors of DNA gyrase B and topoisomerase IV, part I: structure guided… | x-ray diffraction | A, B, C, D, E, F, G, H, J | — | — |
| H7C794 | AlphaFold monomer V2.0 prediction for DNA topoisomerase 4 subunit B (H7C794) | predicted | A | — | 5 (best 0.80) |
Experiment against prediction
- 4HZ5 chain B against the predicted model H7C794: TM-score 0.98, RMSD 0.79 Å
- 4HZ5 chain B against the predicted model H7C794: TM-score 0.98, RMSD 0.79 Å
- 4HZ5 chain A against the predicted model H7C794: TM-score 0.98, RMSD 0.86 Å
- 4HZ5 chain A against the predicted model H7C794: TM-score 0.98, RMSD 0.86 Å
- 4HZ5 chain J against the predicted model H7C794: TM-score 0.98, RMSD 0.81 Å
- 4HZ5 chain J against the predicted model H7C794: TM-score 0.98, RMSD 0.81 Å
- 4HZ5 chain D against the predicted model H7C794: TM-score 0.97, RMSD 0.97 Å
- 4HZ5 chain D against the predicted model H7C794: TM-score 0.97, RMSD 0.97 Å
Elsewhere
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