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UniProt H0VCJ6

N-acylethanolamine acid amidase alpha-subunit (H0VCJ6)

N-acylethanolamine acid amidase alpha-subunit (UniProt H0VCJ6), EC 3.5.1.60: 2 experimental structures and 1 predicted model on GenesisL1, 4 ligands bound, 3 pockets. Binding sites, druggability and experiment against prediction…

UniProt
H0VCJ6
Protein
N-acylethanolamine acid amidase alpha-subunit
EC
3.5.1.60
Experimental structures
2
Predicted models
1
Ligands
4
Pockets
3 · 2 records with a druggable one

Structures

3 records of H0VCJ6 in the MolNFT archive: 2 experimental, 1 predicted.

EntryTitleMethodChainsLigandsPockets
6DY2Guinea pig N-acylethanolamine-hydrolyzing acid amidase (NAAA) covalently bound to beta-lactam…x-ray diffractionA, B, C, DNAG, CL, PO4, HJA2 (best 0.82)
6DY2Guinea pig N-acylethanolamine-hydrolyzing acid amidase (naaa) covalently bound to beta-lactam…x-ray diffractionA, B, C, DNAG, CL, PO4, HJA—
H0VCJ6AlphaFold monomer V2.0 prediction for N-acylethanolamine-hydrolyzing acid amidase (H0VCJ6)predictedA—1 (best 0.67)

Ligands

  • CL · Chloride ion · in 2 records
  • HJA · (2S)-3-amino-2-{[(4-cyclohexylbutoxy) carbonyl]amino}propanethioic S-acid · in 2 records
  • NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · in 2 records
  • PO4 · Phosphate ion · in 2 records

Experiment against prediction

Elsewhere

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