UniProt G7CBF5
Mycobactin import ATP-binding/permease protein IrtA (G7CBF5)
Mycobactin import ATP-binding/permease protein IrtA (UniProt G7CBF5), EC 7.2.2.-: 9 experimental structures and 1 predicted model on GenesisL1, 7 ligands bound, 119 pockets. Binding sites, druggability and experiment against…
- UniProt
- G7CBF5
- Protein
- Mycobactin import ATP-binding/permease protein IrtA
- EC
- 7.2.2.-
- Experimental structures
- 9
- Predicted models
- 1
- Ligands
- 7
- Pockets
- 119 · 10 records with a druggable one
Structures
10 records of G7CBF5 in the MolNFT archive: 9 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 9FW3 | Cryo-EM structure of IrtAB 2xEQ mutant in outward-occluded state in nanodisc in complex with… | electron microscopy | A | ATP, MG, ZN, A1IRY | 9 (best 0.88) |
| 9FXC | Cryo-EM structure of IrtAB in inward-facing state in nanodisc | electron microscopy | A | AGS | 15 (best 0.86) |
| 9G2K | Cryo-EM structure of IrtAB in outward-occluded state in nanodisc in complex with ADP-vanadate | electron microscopy | A | AOV, MG, ZN | 9 (best 0.85) |
| 9G2L | Cryo-EM structure of IrtAB in inward-facing state in LMNG | electron microscopy | A | ZN | 15 (best 0.86) |
| 9G2S | Cryo-EM structure of IrtAB 2xEQ, Q249R_IrtB mutant in LMNG | electron microscopy | A | ATP, MG | 11 (best 0.89) |
| 9G2T | Cryo-EM structure of IrtAB 2xEQ, A256R_IrtB mutant in LMNG | electron microscopy | A | ATP, MG | 13 (best 0.89) |
| 9G2V | Cryo-EM structure of IrtAB in inward-facing state in presence of mycobactin under turnover… | electron microscopy | A | ADP, ZN | 13 (best 0.85) |
| 9G36 | Cryo-EM structure of IrtAB 3xHtoA mutant in inward-facing state in presence of mycobactin under… | electron microscopy | A | ADP | 15 (best 0.84) |
| 9GL3 | Cryo-EM structure of IrtAB 2xEQ, A256R_IrtB mutant in LMNG | electron microscopy | A | ATP | 10 (best 0.88) |
| G7CBF5 | AlphaFold monomer V2.0 prediction for mycobactin import ATP- BINDING/PERMEASE protein irta (G7CBF5) | predicted | A | — | 9 (best 0.75) |
Ligands
Experiment against prediction
- 9G2L chain A against the predicted model G7CBF5: TM-score 0.91, RMSD 2.73 Å
- 9FXC chain A against the predicted model G7CBF5: TM-score 0.90, RMSD 3.00 Å
- 9G36 chain A against the predicted model G7CBF5: TM-score 0.90, RMSD 3.06 Å
- 9G2V chain A against the predicted model G7CBF5: TM-score 0.88, RMSD 3.18 Å
- 9G2S chain A against the predicted model G7CBF5: TM-score 0.81, RMSD 4.12 Å
- 9G2T chain A against the predicted model G7CBF5: TM-score 0.81, RMSD 4.16 Å
- 9GL3 chain A against the predicted model G7CBF5: TM-score 0.81, RMSD 4.19 Å
- 9FW3 chain A against the predicted model G7CBF5: TM-score 0.81, RMSD 4.18 Å
- 9G2K chain A against the predicted model G7CBF5: TM-score 0.81, RMSD 4.30 Å
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.