UniProt G3V9C5
Glutamate receptor (G3V9C5)
Glutamate receptor (UniProt G3V9C5): 8 experimental structures on GenesisL1, 7 ligands bound, 29 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- G3V9C5
- Protein
- Glutamate receptor
- Experimental structures
- 8
- Predicted models
- 0
- Ligands
- 7
- Pockets
- 29 · 6 records with a druggable one
Structures
8 records of G3V9C5 in the MolNFT archive: 8 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5VII | Crystal structure of GluN1/GluN2A NMDA receptor agonist binding domains with glycine and… | x-ray diffraction | B | 5DY | 2 (best 0.80) |
| 5VII | Crystal structure of GLUN1/GLUN2A NMDA receptor agonist binding domains with glycine and… | x-ray diffraction | B | 5DY | — |
| 6ODL | Crystal structure of GluN2A agonist binding domain with 4-butyl-(S)-CCG-IV | x-ray diffraction | A, B | M7V | 4 (best 0.68) |
| 6ODL | Crystal structure of GLUN2A agonist binding domain with 4-butyl-(S)- ccg-IV | x-ray diffraction | A, B | M7V | — |
| 7YFI | Structure of the Rat tri-heteromeric GluN1-GluN2A-GluN2C NMDA receptor in complex with glycine and… | electron microscopy | B | NAG, GLU | 10 (best 0.85) |
| 9GIB | NMDA bound to compound 380 | x-ray diffraction | A | GLU, A1ILP, SO4 | 3 (best 0.78) |
| 9GIG | NMDA bound to compound 387 | x-ray diffraction | A | GLU, A1ILO | 5 (best 0.81) |
| 9GJ1 | NMDA bound to compound 339 | x-ray diffraction | A | GLU | 5 (best 0.81) |
Ligands
- GLU · Glutamic acid · in 4 records
- 5DY · 5-[(2R)-2-amino-2-carboxyethyl]-1-[4-(3-fluoropropyl) phenyl]-1H-pyrazole-3-carboxylic acid · in 2 records
- M7V · (1S,2R)-2-[(S)-amino(carboxy)methyl]-1-butylcyclopropane-1-carboxylic acid · in 2 records
- A1ILO · (2~{R})-2-azanyl-3-[[3-(5-ethyl-3-methyl-1,2-oxazol-4-yl)-5-fluoranyl-phenyl]carbonylamino]propanoic acid · in 1 record
- A1ILP · (2~{R})-2-azanyl-3-[[3-(5-ethyl-1,2-oxazol-4-yl)-5-fluoranyl-phenyl]carbonylamino]propanoic acid · in 1 record
- NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · in 1 record
- SO4 · Sulfate ion · in 1 record
Experiment against prediction
- 6ODL chain A against the predicted model Q00959: TM-score 0.96, RMSD 1.47 Å
- 6ODL chain A against the predicted model Q00959: TM-score 0.96, RMSD 1.47 Å
- 6ODL chain B against the predicted model Q00959: TM-score 0.96, RMSD 1.50 Å
- 6ODL chain B against the predicted model Q00959: TM-score 0.96, RMSD 1.50 Å
- 5VII chain B against the predicted model Q00959: TM-score 0.95, RMSD 1.47 Å
- 5VII chain B against the predicted model Q00959: TM-score 0.95, RMSD 1.47 Å
Elsewhere
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