UniProt G3ECR1
CRISPR-associated endonuclease Cas9 (G3ECR1)
CRISPR-associated endonuclease Cas9 (UniProt G3ECR1), EC 3.1.-.-: 1 experimental structure and 1 predicted model on GenesisL1, 1 ligand bound, 20 pockets. Binding sites, druggability and experiment against prediction (TM-score)…
- UniProt
- G3ECR1
- Protein
- CRISPR-associated endonuclease Cas9
- EC
- 3.1.-.-
- Experimental structures
- 1
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 20 · 1 record with a druggable one
Structures
2 records of G3ECR1 in the MolNFT archive: 1 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 8PJ9 | Cas9 bound to cognate DNA, Streptococcus thermophilus DGCC 7710 CRISPR3 system | electron microscopy | A | MG | 20 (best 0.81) |
| G3ECR1 | AlphaFold monomer V2.0 prediction for CRISPR-associated endonuclease CAS9 (G3ECR1) | predicted | A | — | — |
Ligands
- MG · Magnesium ion · in 1 record
Experiment against prediction
- 8PJ9 chain A against the predicted model G3ECR1: TM-score 0.96, RMSD 2.12 Å
Elsewhere
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