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UniProt G2SLH8

cGAS/DncV-like nucleotidyltransferase in E. coli homolog (G2SLH8)

cGAS/DncV-like nucleotidyltransferase in E. coli homolog (UniProt G2SLH8): 4 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 8 pockets. Binding sites, druggability and experiment against prediction…

UniProt
G2SLH8
Protein
cGAS/DncV-like nucleotidyltransferase in E. coli homolog
Experimental structures
4
Predicted models
1
Ligands
3
Pockets
8 · 4 records with a druggable one

Structures

5 records of G2SLH8 in the MolNFT archive: 4 experimental, 1 predicted.

EntryTitleMethodChainsLigandsPockets
6E0KStructure of Rhodothermus marinus CdnE c-UMP-AMP synthasex-ray diffractionA—2 (best 0.61)
6E0KStructure of rhodothermus marinus cdne C-ump-AMP synthasex-ray diffractionA—2 (best 0.61)
6E0LStructure of Rhodothermus marinus CdnE c-UMP-AMP synthase with Apcpp and Upnppx-ray diffractionAMG, APC, 2KH2 (best 0.65)
6E0LStructure of rhodothermus marinus cdne C-ump-AMP synthase with apcpp and upnppx-ray diffractionAMG, APC, 2KH2 (best 0.65)
G2SLH8AlphaFold monomer V2.0 prediction for cyclic ump-AMP synthase (G2SLH8)predictedA——

Ligands

  • 2KH · 5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]uridine · in 2 records
  • APC · Diphosphomethylphosphonic acid adenosyl ester · in 2 records
  • MG · Magnesium ion · in 2 records

Experiment against prediction

Elsewhere

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