UniProt G2IQQ5
4-oxalomesaconate hydratase (G2IQQ5)
4-oxalomesaconate hydratase (UniProt G2IQQ5), EC 4.2.1.83: 6 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 23 pockets. Binding sites, druggability and experiment against prediction (TM-score) in…
- UniProt
- G2IQQ5
- Protein
- 4-oxalomesaconate hydratase
- EC
- 4.2.1.83
- Experimental structures
- 6
- Predicted models
- 1
- Ligands
- 3
- Pockets
- 23 · 2 records with a druggable one
Structures
7 records of G2IQQ5 in the MolNFT archive: 6 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6DWV | Crystal structure of the LigJ Hydratase in the Apo state | x-ray diffraction | B, A, C, D | ZN | — |
| 6DWV | Crystal structure of the ligj hydratase in the apo state | x-ray diffraction | B, A, C, D | ZN | — |
| 6DXQ | Crystal structure of the LigJ Hydratase product complex with 4-carboxy-4-hydroxy-2-oxoadipate | x-ray diffraction | A, B, C, D | ZN, 7QD | 10 (best 0.69) |
| 6DXQ | Crystal structure of the ligj hydratase product complex with 4- carboxy-4-hydroxy-2-oxoadipate | x-ray diffraction | A, B, C, D | ZN, 7QD | — |
| 6DXS | Crystal structure of the LigJ hydratase E284Q mutant substrate complex with… | x-ray diffraction | A, B, C, D | ZN, HJ7 | 12 (best 0.71) |
| 6DXS | Crystal structure of the ligj hydratase E284Q mutant substrate complex with… | x-ray diffraction | A, B, C, D | ZN, HJ7 | — |
| G2IQQ5 | AlphaFold monomer V2.0 prediction for 2-keto-4-carboxy-3-hexenedioate hydratase (G2IQQ5) | predicted | A | — | 1 (best 0.42) |
Ligands
Experiment against prediction
- 6DXQ chain A against the predicted model G2IQQ5: TM-score 1.00, RMSD 0.32 Å
- 6DXQ chain A against the predicted model G2IQQ5: TM-score 1.00, RMSD 0.32 Å
- 6DWV chain B against the predicted model G2IQQ5: TM-score 1.00, RMSD 0.34 Å
- 6DWV chain B against the predicted model G2IQQ5: TM-score 1.00, RMSD 0.34 Å
- 6DXQ chain B against the predicted model G2IQQ5: TM-score 1.00, RMSD 0.35 Å
- 6DXQ chain B against the predicted model G2IQQ5: TM-score 1.00, RMSD 0.35 Å
- 6DXQ chain D against the predicted model G2IQQ5: TM-score 1.00, RMSD 0.36 Å
- 6DXQ chain D against the predicted model G2IQQ5: TM-score 1.00, RMSD 0.36 Å
- 6DXQ chain C against the predicted model G2IQQ5: TM-score 1.00, RMSD 0.36 Å
- 6DXQ chain C against the predicted model G2IQQ5: TM-score 1.00, RMSD 0.36 Å
Elsewhere
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