UniProt G2FID1
Cys-loop ligand-gated ion channel (G2FID1)
Cys-loop ligand-gated ion channel (UniProt G2FID1): 10 experimental structures on GenesisL1, 4 ligands bound, 80 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- G2FID1
- Protein
- Cys-loop ligand-gated ion channel
- Experimental structures
- 10
- Predicted models
- 0
- Ligands
- 4
- Pockets
- 80 · 4 records with a druggable one
Structures
10 records of G2FID1 in the MolNFT archive: 10 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6FL9 | The active form of a pentameric ion channel (sTeLIC) gated by alkaline pH - Wild type 2.3 Angstrom… | x-ray diffraction | A, B, C, D, E | BNG | 20 (best 0.83) |
| 6FL9 | The active form of a pentameric ion channel (stelic) gated by alkaline pH - wild type 2.3 ångström… | x-ray diffraction | A, B, C, D, E | BNG | — |
| 6FLI | The active form of a pentameric ion channel (sTeLIC) gated by alkaline pH - Co-crystallization with… | x-ray diffraction | A, B, C, D, E | BNG, DQZ | 20 (best 0.81) |
| 6FLI | The active form of a pentameric ion channel (stelic) gated by alkaline pH - co-crystallization with… | x-ray diffraction | A, B, C, D, E | BNG, DQZ | — |
| 6FVQ | The active form of a pentameric ion channel (sTeLIC) gated by alkaline pH - R86A | x-ray diffraction | A, B, C, D, E | BNG | 20 (best 0.80) |
| 6FVQ | The active form of a pentameric ion channel (stelic) gated by alkaline pH - R86A | x-ray diffraction | A, B, C, D, E | BNG | — |
| 6FVR | The active form of a pentameric ion channel (sTeLIC) gated by alkaline pH - sTeLIC in complex with… | x-ray diffraction | A, B, C, D, E | BNG, CS | — |
| 6FVR | The active form of a pentameric ion channel (stelic) gated by alkaline pH - stelic in complex with… | x-ray diffraction | A, B, C, D, E | BNG, CS | — |
| 6FVS | The active form of a pentameric ion channel (sTeLIC) gated by alkaline pH - sTeLIC in complex with… | x-ray diffraction | A, B, C, D, E | BNG, ZN | 20 (best 0.74) |
| 6FVS | The active form of a pentameric ion channel (stelic) gated by alkaline pH - stelic in complex with… | x-ray diffraction | A, B, C, D, E | BNG, ZN | — |
Ligands
Elsewhere
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