UniProt G0X8E3
HIV-1 protease (G0X8E3)
HIV-1 protease (UniProt G0X8E3): 8 experimental structures on GenesisL1, 4 ligands bound, 6 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- G0X8E3
- Protein
- HIV-1 protease
- Experimental structures
- 8
- Predicted models
- 0
- Ligands
- 4
- Pockets
- 6 · 4 records with a druggable one
Structures
8 records of G0X8E3 in the MolNFT archive: 8 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5COK | X-ray crystal structure of wild type HIV-1 protease in complex with GRL-0476 | x-ray diffraction | A, B | 52U | 2 (best 0.72) |
| 5COK | X-ray crystal structure of wild type HIV-1 protease in complex with grl-0476 | x-ray diffraction | A, B | — | — |
| 5CON | X-ray crystal structure of wild type HIV-1 protease in complex with GRL-015 | x-ray diffraction | A, B | 52W | 1 (best 0.72) |
| 5CON | X-ray crystal structure of wild type HIV-1 protease in complex with grl-015 | x-ray diffraction | A, B | — | — |
| 5COO | X-ray crystal structure of wild type HIV-1 protease in complex with GRL-085 | x-ray diffraction | A, B | 52Z | 2 (best 0.69) |
| 5COO | X-ray crystal structure of wild type HIV-1 protease in complex with grl-085 | x-ray diffraction | A, B | — | — |
| 5COP | X-ray crystal structure of wild type HIV-1 protease in complex with GRL-097 | x-ray diffraction | A, B | 53F | 1 (best 0.71) |
| 5COP | X-ray crystal structure of wild type HIV-1 protease in complex with grl-097 | x-ray diffraction | A, B | — | — |
Ligands
- 52U · (3aS,4S,7aR)-hexahydro-4H-furo[2,3-b]pyran-4-yl [(2S,3R)-3-hydroxy-4-{[(4-methoxyphenyl)sulfonyl](2-methylpropyl)amino}-1-phenylbutan-2-yl]carbamate · in 1 record
- 52W · (3R,3aS,4S,7aS)-3-hydroxyhexahydro-4H-furo[2,3-b]pyran-4-yl [(2S,3R)-3-hydroxy-4-{[(4-methoxyphenyl)sulfonyl](2-methylpropyl)amino}-1-phenylbutan-2-yl]carbamate · in 1 record
- 52Z · (3R,3aS,4S,7aS)-3-hydroxyhexahydro-4H-furo[2,3-b]pyran-4-yl [(2S,3R)-3-hydroxy-1-(4-methoxyphenyl)-4-{[(4-methoxyphenyl)sulfonyl](2-methylpropyl)amino}butan-2-yl]carbamate · in 1 record
- 53F · (3R,3aS,4S,7aS)-3-hydroxyhexahydro-4H-furo[2,3-b]pyran-4-yl [(2S,3R)-4-{[(4-aminophenyl)sulfonyl](2-methylpropyl)amino}-3-hydroxy-1-(4-methoxyphenyl)butan-2-yl]carbamate · in 1 record
Elsewhere
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