UniProt G0SCK6
Ribosome biogenesis protein ERB1 (G0SCK6)
Ribosome biogenesis protein ERB1 (UniProt G0SCK6): 12 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 17 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- G0SCK6
- Protein
- Ribosome biogenesis protein ERB1
- Experimental structures
- 12
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 17 · 7 records with a druggable one
Structures
13 records of G0SCK6 in the MolNFT archive: 12 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5CXB | Structure of YTM1 bound to the C-terminal domain of ERB1 in P21 21 2 space group | x-ray diffraction | B | — | — |
| 5CXC | Structure of YTM1 bound to the C-terminal domain of ERB1 in P 65 2 2 space group | x-ray diffraction | B | — | — |
| 5CYK | Structure of YTM1 bound to the C-terminal domain of ERB1-R486E | x-ray diffraction | B | — | — |
| 5EM2 | Crystal structure of the Erb1-Ytm1 complex | x-ray diffraction | A, C | MG | — |
| 5EM2 | Crystal structure of the ERB1-YTM1 complex | x-ray diffraction | A, C | — | — |
| 8I9P | Cryo-EM structure of a Chaetomium thermophilum pre-60S ribosomal subunit - State Mak16 | electron microscopy | CC | — | 1 (best 0.88) |
| 8I9T | Cryo-EM structure of a Chaetomium thermophilum pre-60S ribosomal subunit - State Dbp10-1 | electron microscopy | CC | — | 2 (best 0.89) |
| 8I9V | Cryo-EM structure of a Chaetomium thermophilum pre-60S ribosomal subunit - State Dbp10-2 | electron microscopy | CC | — | 1 (best 0.87) |
| 8I9X | Cryo-EM structure of a Chaetomium thermophilum pre-60S ribosomal subunit - Ytm1-1 | electron microscopy | CC | — | 3 (best 0.88) |
| 8I9Y | Cryo-EM structure of a Chaetomium thermophilum pre-60S ribosomal subunit - Ytm1-2 | electron microscopy | CC | — | 5 (best 0.89) |
| 8I9Z | Cryo-EM structure of a Chaetomium thermophilum pre-60S ribosomal subunit - State Spb4 | electron microscopy | CC | — | 3 (best 0.89) |
| 8PV2 | Chaetomium thermophilum pre-60S State 10 - pre-5S rotation with Ytm1-Erb1 | electron microscopy | CC | — | 2 (best 0.87) |
| G0SCK6 | AlphaFold monomer V2.0 prediction for ribosome biogenesis protein ERB1 (G0SCK6) | predicted | A | — | — |
Ligands
- MG · Magnesium ion · in 1 record
Experiment against prediction
- 5CXB chain B against the predicted model G0SCK6: TM-score 1.00, RMSD 0.37 Å
- 5CXC chain B against the predicted model G0SCK6: TM-score 0.99, RMSD 0.62 Å
- 5CYK chain B against the predicted model G0SCK6: TM-score 0.99, RMSD 0.70 Å
- 5EM2 chain A against the predicted model G0SCK6: TM-score 0.99, RMSD 0.82 Å
- 5EM2 chain A against the predicted model G0SCK6: TM-score 0.99, RMSD 0.82 Å
- 5EM2 chain C against the predicted model G0SCK6: TM-score 0.99, RMSD 0.83 Å
- 5EM2 chain C against the predicted model G0SCK6: TM-score 0.99, RMSD 0.83 Å
- 8PV2 chain CC against the predicted model G0SCK6: TM-score 0.90, RMSD 2.32 Å
- 8I9Z chain CC against the predicted model G0SCK6: TM-score 0.72, RMSD 3.32 Å
- 8I9Y chain CC against the predicted model G0SCK6: TM-score 0.72, RMSD 3.17 Å
Elsewhere
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