UniProt G0S8H7
Polycomb Protein EED (G0S8H7)
Polycomb Protein EED (UniProt G0S8H7): 20 experimental structures on GenesisL1, 1 ligand bound, 105 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- G0S8H7
- Protein
- Polycomb Protein EED
- Experimental structures
- 20
- Predicted models
- 0
- Ligands
- 1
- Pockets
- 105 · 9 records with a druggable one
Structures
20 records of G0S8H7 in the MolNFT archive: 20 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5BJS | Apo ctPRC2 in an autoinhibited state | x-ray diffraction | A | — | 13 (best 0.86) |
| 5BJS | Apo CTPRC2 in an autoinhibited state | x-ray diffraction | A | — | — |
| 5KJH | Crystal structure of an active polycomb repressive complex 2 in the stimulated state | x-ray diffraction | A | — | 12 (best 0.86) |
| 5KJH | Crystal structure of an active polycomb repressive complex 2 in the stimulated state | x-ray diffraction | A | — | — |
| 5KJI | Crystal structure of an active polycomb repressive complex 2 in the basal state | x-ray diffraction | A | — | 11 (best 0.86) |
| 5KJI | Crystal structure of an active polycomb repressive complex 2 in the basal state | x-ray diffraction | A | — | — |
| 5KKL | Structure of ctPRC2 in complex with H3K27me3 and H3K27M | x-ray diffraction | A | — | 12 (best 0.87) |
| 5KKL | Structure of CTPRC2 in complex with H3K27ME3 and H3K27M | x-ray diffraction | A | — | — |
| 5M5G | Crystal structure of the Chaetomium Thermophilum polycomb repressive complex 2 (PRC2) | x-ray diffraction | A | — | 13 (best 0.86) |
| 5M5G | Crystal structure of the chaetomium thermophilum polycomb repressive complex 2 (PRC2) | x-ray diffraction | A | — | — |
| 5TQR | ctPRC2 in an autoinhibited conformation bound to S-adenosylmethionine | x-ray diffraction | A | — | 14 (best 0.86) |
| 5TQR | CTPRC2 in an autoinhibited conformation bound to S-adenosylmethionine | x-ray diffraction | A | — | — |
| 5VK3 | Apo ctPRC2 with E840A and K852D mutations in Ezh2 | x-ray diffraction | A | — | — |
| 5VK3 | Apo CTPRC2 with E840A and K852D mutations in EZH2 | x-ray diffraction | A | — | — |
| 5WF7 | Chaetomium thermophilum Polycomb Repressive Complex 2 bound to GSK126 | x-ray diffraction | A | — | — |
| 5WF7 | Chaetomium thermophilum polycomb repressive complex 2 bound to GSK126 | x-ray diffraction | A | A9G | 11 (best 0.85) |
| 5WFC | Humanized mutant of the Chaetomium thermophilum Polycomb Repressive Complex 2 bound to the… | x-ray diffraction | A | — | 9 (best 0.85) |
| 5WFC | Humanized mutant of the chaetomium thermophilum polycomb repressive complex 2 bound to the… | x-ray diffraction | A | — | — |
| 5WFD | Humanized mutant of the Chaetomium thermophilum Polycomb Repressive Complex 2 bound to the… | x-ray diffraction | A | — | 10 (best 0.85) |
| 5WFD | Humanized mutant of the chaetomium thermophilum polycomb repressive complex 2 bound to the… | x-ray diffraction | A | — | — |
Ligands
- A9G · 1-[(2S)-butan-2-yl]-N-[(4,6-dimethyl-2-oxo-1,2-dihydropyridin-3-yl)methyl]-3-methyl-6-[6-(piperazin-1-yl)pyridin-3-yl]-1H-indole-4-carboxamide · in 1 record
Elsewhere
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