UniProt G0RY84
Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP43 (G0RY84)
Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP43 (UniProt G0RY84), EC 3.6.4.13: 11 experimental structures on GenesisL1, 5 ligands bound, 32 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- G0RY84
- Protein
- Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP43
- EC
- 3.6.4.13
- Experimental structures
- 11
- Predicted models
- 0
- Ligands
- 5
- Pockets
- 32 · 4 records with a druggable one
Structures
11 records of G0RY84 in the MolNFT archive: 11 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5D0U | Crystal structure of the RNA-helicase Prp43 from Chaetomium thermophilum bound to ADP | x-ray diffraction | A | ADP, MG | 8 (best 0.84) |
| 5D0U | Crystal structure of the RNA-helicase PRP43 from chaetomium thermophilum bound to ADP | x-ray diffraction | A | — | — |
| 5LTA | Crystal structure of the Prp43-ADP-BeF3-U7-RNA complex | x-ray diffraction | A | ADP, MG, BEF | 9 (best 0.86) |
| 5LTA | Crystal structure of the PRP43-ADP-BEF3-U7-RNA complex | x-ray diffraction | A | ADP, MG, BEF | — |
| 5LTJ | Crystal structure of the Prp43-ADP-BeF3 complex (in orthorhombic space group) | x-ray diffraction | A | ADP, BEF, MG, SO4, CL | 7 (best 0.72) |
| 5LTJ | Crystal structure of the PRP43-ADP-BEF3 complex (in orthorhombic space group) | x-ray diffraction | A | ADP, BEF, MG, SO4, CL | — |
| 5LTK | Crystal structure of the Prp43-ADP-BeF3 complex (in hexagonal space group) | x-ray diffraction | A | ADP, BEF, MG, SO4 | 8 (best 0.76) |
| 5LTK | Crystal structure of the PRP43-ADP-BEF3 complex (in hexagonal space group) | x-ray diffraction | A | ADP, BEF, MG, SO4 | — |
| 6QID | Crystal structure of DEAH-box ATPase Prp43-S387A | x-ray diffraction | A | CL, MG, SO4, ADP, BEF | — |
| 6QID | Crystal structure of deah-box ATPase PRP43-S387A | x-ray diffraction | A | CL, MG, SO4, ADP, BEF | — |
| 6QIE | Crystal structure of deah-box ATPase PRP43-S387G | x-ray diffraction | A | ADP, CL, SO4, MG, BEF | — |
Ligands
Elsewhere
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