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UniProt F2Q7T0

Bifunctional cytochrome P450/NADPH--P450 reductase (F2Q7T0)

Bifunctional cytochrome P450/NADPH--P450 reductase (UniProt F2Q7T0), EC 1.14.14.1, 1.6.2.4: 9 experimental structures on GenesisL1, 9 ligands bound, 63 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.

UniProt
F2Q7T0
Protein
Bifunctional cytochrome P450/NADPH--P450 reductase
EC
1.14.14.1, 1.6.2.4
Experimental structures
9
Predicted models
0
Ligands
9
Pockets
63 · 6 records with a druggable one

Structures

9 records of F2Q7T0 in the MolNFT archive: 9 experimental, 0 predicted.

EntryTitleMethodChainsLigandsPockets
5OG9The BM3 mutant WIFI-WC heme domain in complex with testosteronex-ray diffractionA, BHEM, ZN, TES, CL5 (best 0.88)
5OG9The BM3 mutant wifi-wc heme domain in complex with testosteronex-ray diffractionA, BHEM, ZN, TES, CL—
5UCWCytochrome P411 P-4 A82L A78V F263L amination catalystx-ray diffractionA, BHEM9 (best 0.88)
5UCWCytochrome P411 P-4 A82L A78V F263L amination catalystx-ray diffractionA, BHEM—
6H1LStructure of the BM3 heme domain in complex with tioconazolex-ray diffractionA, BFJQ, HEM, PO49 (best 0.86)
6H1LStructure of the BM3 heme domain in complex with tioconazolex-ray diffractionA, BFJQ, HEM, PO49 (best 0.86)
6K24Structure of the Rhodium Mesoporphyrin IX-Reconstituted CYP102A1 Haem Domain with…x-ray diffractionA, BWAA, CV011 (best 0.87)
6K24Structure of the rhodium mesoporphyrin IX-reconstituted CYP102A1 haem domain with…x-ray diffractionA, BCV0—
8DSGP411-PFA carbene transferasex-ray diffractionA, B, C, DHEM, SO420 (best 0.88)

Ligands

  • HEM · Protoporphyrin IX containing Fe · in 7 records
  • CL · Chloride ion · in 2 records
  • CV0 · MESOPORPHYRIN IX CONTAINING Rh · in 2 records
  • FJQ · Tioconazole · in 2 records
  • PO4 · Phosphate ion · in 2 records
  • TES · Testosterone · in 2 records
  • ZN · Zinc ion · in 2 records
  • SO4 · Sulfate ion · in 1 record
  • WAA · (2S)-2-[[(1R,4aR,4bR,10aR)-1,4a-dimethyl-7-propan-2-yl-2,3,4,4b,5,6,10,10a-octahydrophenanthren-1-yl]carbonylamino]-3-( 1H-indol-3-yl)propanoic acid · in 1 record

Elsewhere

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