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UniProt F1PJP5

Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A (F1PJP5)

Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A (UniProt F1PJP5), EC 2.4.99.18: 3 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 7 pockets. Binding sites, druggability…

UniProt
F1PJP5
Protein
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A
EC
2.4.99.18
Experimental structures
3
Predicted models
1
Ligands
2
Pockets
7 · 1 record with a druggable one

Structures

4 records of F1PJP5 in the MolNFT archive: 3 experimental, 1 predicted.

EntryTitleMethodChainsLigandsPockets
6FTGSubtomogram average of OST-containing ribosome-translocon complexes from canine rough microsomal…electron microscopy5NAG, 9UB—
6FTICryo-EM Structure of the Mammalian Oligosaccharyltransferase Bound to Sec61 and the Programmed 80S…electron microscopy5NAG, 9UB—
6FTJCryo-EM Structure of the Mammalian Oligosaccharyltransferase Bound to Sec61 and the Non-programmed…electron microscopy5NAG, 9UB—
F1PJP5AlphaFold monomer V2.0 prediction for dolichyl- diphosphooligosaccharide--protein…predictedA—7 (best 0.80)

Ligands

  • 9UB · [(2~{S},3~{R},4~{R},5~{S},6~{R})-3-acetamido-6-(hydroxymethyl)-4,5-bis(oxidanyl)oxan-2-yl]methyl-[oxidanyl-[(2~{Z},6~{Z},10~{Z})-3,7,11,15-tetramethylhexadeca-2,6,10,14-tetraenoxy]phosphoryl]oxy-phosphinic acid · in 3 records
  • NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · in 3 records

Experiment against prediction

Elsewhere

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