UniProt F1P963
MTH1 protein (F1P963)
MTH1 protein (UniProt F1P963): 2 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 24 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- F1P963
- Protein
- MTH1 protein
- Experimental structures
- 2
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 24 · 2 records with a druggable one
Structures
3 records of F1P963 in the MolNFT archive: 2 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5MZF | Crystal structure of dog MTH1 protein | x-ray diffraction | A, B, C, D | SO4, CL | 12 (best 0.71) |
| 5MZF | Crystal structure of dog MTH1 protein | x-ray diffraction | A, B, C, D | SO4, CL | 12 (best 0.71) |
| F1P963 | AlphaFold monomer V2.0 prediction for 7,8-dihydro-8-oxoguanine triphosphatase (F1P963) | predicted | A | — | — |
Ligands
Experiment against prediction
- 5MZF chain C against the predicted model F1P963: TM-score 0.99, RMSD 0.39 Å
- 5MZF chain C against the predicted model F1P963: TM-score 0.99, RMSD 0.39 Å
- 5MZF chain B against the predicted model F1P963: TM-score 0.94, RMSD 0.58 Å
- 5MZF chain B against the predicted model F1P963: TM-score 0.94, RMSD 0.58 Å
- 5MZF chain A against the predicted model F1P963: TM-score 0.98, RMSD 0.62 Å
- 5MZF chain A against the predicted model F1P963: TM-score 0.98, RMSD 0.62 Å
- 5MZF chain D against the predicted model F1P963: TM-score 0.93, RMSD 0.43 Å
- 5MZF chain D against the predicted model F1P963: TM-score 0.93, RMSD 0.43 Å
Elsewhere
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