UniProt F0ZBA6
Nicastrin (F0ZBA6)
Nicastrin (UniProt F0ZBA6): 2 experimental structures and 1 predicted model on GenesisL1, 5 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- F0ZBA6
- Protein
- Nicastrin
- Experimental structures
- 2
- Predicted models
- 1
- Pockets
- 5 · 1 record with a druggable one
Structures
3 records of F0ZBA6 in the MolNFT archive: 2 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4R12 | Crystal structure of the gamma-secretase component Nicastrin | x-ray diffraction | A | — | — |
| 4R12 | Crystal structure of the gamma-secretase component nicastrin | x-ray diffraction | A | — | — |
| F0ZBA6 | AlphaFold monomer V2.0 prediction for nicastrin (F0ZBA6) | predicted | A | — | 5 (best 0.56) |
Experiment against prediction
- 4R12 chain A against the predicted model F0ZBA6: TM-score 1.00, RMSD 0.19 Å
- 4R12 chain A against the predicted model F0ZBA6: TM-score 1.00, RMSD 0.19 Å
Elsewhere
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