UniProt E9QY26
14-alpha sterol demethylase Cyp51B (E9QY26)
14-alpha sterol demethylase Cyp51B (UniProt E9QY26), EC 1.14.13.70: 2 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 14 pockets. Binding sites, druggability and experiment against prediction…
- UniProt
- E9QY26
- Protein
- 14-alpha sterol demethylase Cyp51B
- EC
- 1.14.13.70
- Experimental structures
- 2
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 14 · 1 record with a druggable one
Structures
3 records of E9QY26 in the MolNFT archive: 2 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6CR2 | Crystal structure of sterol 14-alpha demethylase (CYP51B) from Aspergillus fumigatus in complex… | x-ray diffraction | A, B | HEM, LFV | 14 (best 0.86) |
| 6CR2 | Crystal structure of sterol 14-alpha demethylase (CYP51B) from aspergillus fumigatus in complex… | x-ray diffraction | A, B | HEM, LFV | — |
| E9QY26 | AlphaFold monomer V2.0 prediction for sterol 14-alpha demethylase (E9QY26) | predicted | A | — | — |
Ligands
Experiment against prediction
- 6CR2 chain B against the predicted model E9QY26: TM-score 0.99, RMSD 1.11 Å
- 6CR2 chain B against the predicted model E9QY26: TM-score 0.99, RMSD 1.11 Å
- 6CR2 chain A against the predicted model E9QY26: TM-score 0.99, RMSD 1.13 Å
- 6CR2 chain A against the predicted model E9QY26: TM-score 0.99, RMSD 1.13 Å
Elsewhere
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