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UniProt E7EQ52

Poly [ADP-ribose] polymerase (E7EQ52)

Poly [ADP-ribose] polymerase (UniProt E7EQ52), EC 2.4.2.-: 3 experimental structures on GenesisL1, 2 ligands bound, 5 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.

UniProt
E7EQ52
Protein
Poly [ADP-ribose] polymerase
EC
2.4.2.-
Experimental structures
3
Predicted models
0
Ligands
2
Pockets
5 · 2 records with a druggable one

Structures

3 records of E7EQ52 in the MolNFT archive: 3 experimental, 0 predicted.

EntryTitleMethodChainsLigandsPockets
7OCVHuman TNKS1 in complex with 3-[4-(1-Hydroxy-1-methyl-ethyl)-phenyl]-6-methyl-2H-pyrrolo[1,2-a]pyrazi…x-ray diffractionAV8B, ZN1 (best 0.65)
7OCVHuman TNKS1 in complex with 3-[4-(1-hydroxy-1-methyl-ethyl)-phenyl]-6…x-ray diffractionAV8B, ZN—
8X5JThe Crystal Structure of PARP5A from Biortus.x-ray diffractionA, BZN4 (best 0.83)

Ligands

  • ZN · Zinc ion · in 3 records
  • V8B · 6-methyl-3-[4-(2-oxidanylpropan-2-yl)phenyl]-4~{H}-pyrrolo[1,2-a]pyrazin-1-one · in 2 records

Elsewhere

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