UniProt E7E815
3C protein (E7E815)
3C protein (UniProt E7E815): 16 experimental structures on GenesisL1, 5 ligands bound, 15 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- E7E815
- Protein
- 3C protein
- Experimental structures
- 16
- Predicted models
- 0
- Ligands
- 5
- Pockets
- 15 · 3 records with a druggable one
Structures
16 records of E7E815 in the MolNFT archive: 16 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3QZQ | Human enterovirus 71 3C protease mutant E71D in complex with rupintrivir | x-ray diffraction | A, B, C, D | — | — |
| 3QZQ | Human enterovirus 71 3C protease mutant E71D in complex with rupintrivir | x-ray diffraction | A, B, C, D | — | — |
| 3QZR | Human enterovirus 71 3C protease mutant E71A in complex with rupintrivir | x-ray diffraction | A, B | — | — |
| 3QZR | Human enterovirus 71 3C protease mutant E71A in complex with rupintrivir | x-ray diffraction | A, B | — | — |
| 3R0F | Human enterovirus 71 3C protease mutant H133G in complex with rupintrivir | x-ray diffraction | A, B | — | — |
| 3R0F | Human enterovirus 71 3C protease mutant H133G in complex with rupintrivir | x-ray diffraction | A, B | — | — |
| 5GSO | Crystal Structures of EV71 3C Protease in complex with NK-1.8k | x-ray diffraction | A, B, C, D, E | 5GI | — |
| 5GSO | Crystal structures of EV71 3C protease in complex with nk-1.8K | x-ray diffraction | A, B, C, D, E | — | — |
| 5GSW | Crystal structure of EV71 3C in complex with N69S 1.8k | x-ray diffraction | A, B, C, D, E | 5GI | 11 (best 0.56) |
| 5GSW | Crystal structure of EV71 3C in complex with N69S 1.8K | x-ray diffraction | A, B, C, D, E | — | — |
| 5WQ2 | Crystal structure of 3C protease from a mild Human enterovirus 71 in complex with rupintrivir | x-ray diffraction | A | AG7, SO4 | — |
| 5WQ2 | Crystal structure of 3C protease from a mild human enterovirus 71 in complex with rupintrivir | x-ray diffraction | A | AG7, SO4 | — |
| 7WYL | Structure of the EV71 3Cpro with 337 inhibitor | x-ray diffraction | A, B | G7L | 2 (best 0.63) |
| 7WYL | Structure of the EV71 3CPRO with 337 inhibitor | x-ray diffraction | A, B | G7L | — |
| 7WYO | Structure of the EV71 3Cpro with 338 inhibitor | x-ray diffraction | A, B | G7F | 2 (best 0.60) |
| 7WYO | Structure of the EV71 3CPRO with 338 inhibitor | x-ray diffraction | A, B | G7F | — |
Ligands
- 5GI · ~{N}-[(2~{S})-3-(4-fluorophenyl)-1-oxidanylidene-1-[[(2~{S})-1-oxidanylidene-3-[(3~{S})-2-oxidanylidenepiperidin-3-yl]propan-2-yl]amino]propan-2-yl]-5-methyl-1,2-oxazole-3-carboxamide · in 2 records
- AG7 · 4-{2-(4-fluoro-benzyl)-6-methyl-5-[(5-methyl-isoxazole-3-carbonyl)-amino]-4-oxo-heptanoylamino}-5-(2-oxo-pyrrolidin-3-yl)-pentanoic acid ethyl ester · in 2 records
- G7F · N-methyl-N-(4,5,6,7-tetrahydro-1,3-benzothiazol-2-ylmethyl)prop-2-enamide · in 2 records
- G7L · N-methyl-N-[[4-(trifluoromethyl)-1,3-thiazol-2-yl]methyl]prop-2-enamide · in 2 records
- SO4 · Sulfate ion · in 2 records
Elsewhere
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