UniProt E6LHV2
CRISPR system endoribonuclease Csm6 (E6LHV2)
CRISPR system endoribonuclease Csm6 (UniProt E6LHV2), EC 3.1.-.-: 2 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 20 pockets. Binding sites, druggability and experiment against prediction (TM-score)…
- UniProt
- E6LHV2
- Protein
- CRISPR system endoribonuclease Csm6
- EC
- 3.1.-.-
- Experimental structures
- 2
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 20 · 1 record with a druggable one
Structures
3 records of E6LHV2 in the MolNFT archive: 2 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6TUG | Enterococcus italicus Csm6 bound to cyclic hexa-2'-fluoro-hexa-dAMP | x-ray diffraction | A, B, C, D, E, F, G, H | AF2, SO4 | 20 (best 0.84) |
| 6TUG | Enterococcus italicus CSM6 bound to cyclic hexa-2'-fluoro-hexa-damp | x-ray diffraction | A, B, C, D, E, F, G, H | AF2, SO4 | — |
| E6LHV2 | AlphaFold monomer V2.0 prediction for CRISPR system endoribonuclease CSM6 (E6LHV2) | predicted | A | — | — |
Ligands
Experiment against prediction
- 6TUG chain H against the predicted model E6LHV2: TM-score 0.72, RMSD 4.39 Å
- 6TUG chain H against the predicted model E6LHV2: TM-score 0.72, RMSD 4.39 Å
- 6TUG chain B against the predicted model E6LHV2: TM-score 0.72, RMSD 4.36 Å
- 6TUG chain B against the predicted model E6LHV2: TM-score 0.72, RMSD 4.36 Å
- 6TUG chain F against the predicted model E6LHV2: TM-score 0.72, RMSD 4.38 Å
- 6TUG chain F against the predicted model E6LHV2: TM-score 0.72, RMSD 4.38 Å
- 6TUG chain D against the predicted model E6LHV2: TM-score 0.72, RMSD 4.52 Å
- 6TUG chain D against the predicted model E6LHV2: TM-score 0.72, RMSD 4.52 Å
- 6TUG chain C against the predicted model E6LHV2: TM-score 0.71, RMSD 4.39 Å
- 6TUG chain C against the predicted model E6LHV2: TM-score 0.71, RMSD 4.39 Å
Elsewhere
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