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UniProt E5D8F2

protease 2A (E5D8F2)

protease 2A (UniProt E5D8F2), EC 2.7.7.48, 3.4.22.28: 10 experimental structures on GenesisL1, 2 ligands bound, 28 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.

UniProt
E5D8F2
Protein
protease 2A
EC
2.7.7.48, 3.4.22.28, 3.4.22.29, 3.6.1.15
Experimental structures
10
Predicted models
0
Ligands
2
Pockets
28 · 3 records with a druggable one

Structures

10 records of E5D8F2 in the MolNFT archive: 10 experimental, 0 predicted.

EntryTitleMethodChainsLigandsPockets
5JZGCryoem structure of the native empty particle of a human rhinovirus Celectron microscopyA, B, C——
5K0UCryoem structure of the full virion of a human rhinovirus Celectron microscopyA, B, C, D——
5X45Crystal structure of 2A protease from Human rhinovirus C15x-ray diffractionA, B, C, DZN8 (best 0.60)
5X45Crystal structure of 2A protease from human rhinovirus C15x-ray diffractionA, B, C, DZN—
6KU8structure of HRV-C 3C protein with rupintrivirx-ray diffractionAAG7—
6KU8Structure of hrv-C 3C protein with rupintrivirx-ray diffractionAAG7—
6PPORhinovirus C15 complexed with domain I of receptor CDHR3electron microscopyA, B, C, D—8 (best 0.63)
6PPORhinovirus C15 complexed with domain I of receptor CDHR3electron microscopyA, B, C, D——
6PSFRhinovirus C15 complexed with domains I and II of receptor CDHR3electron microscopyA, B, C, D—12 (best 0.69)
6PSFRhinovirus C15 complexed with domains I and II of receptor CDHR3electron microscopyA, B, C, D——

Ligands

  • AG7 · 4-{2-(4-fluoro-benzyl)-6-methyl-5-[(5-methyl-isoxazole-3-carbonyl)-amino]-4-oxo-heptanoylamino}-5-(2-oxo-pyrrolidin-3-yl)-pentanoic acid ethyl ester · in 2 records
  • ZN · Zinc ion · in 2 records

Elsewhere

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