UniProt E4TN31
TMEM175 (E4TN31)
TMEM175 (UniProt E4TN31): 12 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 18 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- E4TN31
- Protein
- TMEM175
- Experimental structures
- 12
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 18 · 4 records with a druggable one
Structures
13 records of E4TN31 in the MolNFT archive: 12 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6HD8 | Crystal structure of the potassium channel MtTMEM175 in complex with a Nanobody-MBP fusion protein | x-ray diffraction | B | — | — |
| 6HD8 | Crystal structure of the potassium channel MTTMEM175 in complex with a nanobody-mbp fusion protein | x-ray diffraction | B | — | — |
| 6HD9 | Crystal structure of the potassium channel MtTMEM175 with rubidium | x-ray diffraction | B | — | — |
| 6HD9 | Crystal structure of the potassium channel MTTMEM175 with rubidium | x-ray diffraction | B | — | — |
| 6HDA | Crystal structure of the potassium channel MtTMEM175 with cesium | x-ray diffraction | B | — | 3 (best 0.67) |
| 6HDA | Crystal structure of the potassium channel MTTMEM175 with cesium | x-ray diffraction | B | — | — |
| 6HDB | Crystal structure of the potassium channel MtTMEM175 with zinc | x-ray diffraction | B | K, ZN | 4 (best 0.68) |
| 6HDB | Crystal structure of the potassium channel MTTMEM175 with zinc | x-ray diffraction | B | ZN | — |
| 6HDC | Crystal structure of the potassium channel MtTMEM175 T38A variant in complex with a Nanobody-MBP… | x-ray diffraction | B | — | — |
| 6HDC | Crystal structure of the potassium channel MTTMEM175 T38A variant in complex with a nanobody-mbp… | x-ray diffraction | B | — | — |
| 6SWR | Crystal structure of the lysosomal potassium channel MtTMEM175 T38A mutant soaked with zinc | x-ray diffraction | B, E | — | 10 (best 0.71) |
| 6SWR | Crystal structure of the lysosomal potassium channel MTTMEM175 T38A mutant soaked with zinc | x-ray diffraction | B, E | — | — |
| E4TN31 | AlphaFold monomer V2.0 prediction for potassium channel FTRAC_2467 (E4TN31) | predicted | A | — | 1 (best 0.70) |
Ligands
Experiment against prediction
- 6SWR chain B against the predicted model E4TN31: TM-score 0.93, RMSD 1.70 Å
- 6SWR chain B against the predicted model E4TN31: TM-score 0.93, RMSD 1.70 Å
- 6SWR chain E against the predicted model E4TN31: TM-score 0.93, RMSD 1.71 Å
- 6SWR chain E against the predicted model E4TN31: TM-score 0.93, RMSD 1.71 Å
- 6HDA chain B against the predicted model E4TN31: TM-score 0.89, RMSD 2.26 Å
- 6HDA chain B against the predicted model E4TN31: TM-score 0.89, RMSD 2.26 Å
- 6HD8 chain B against the predicted model E4TN31: TM-score 0.89, RMSD 2.29 Å
- 6HD8 chain B against the predicted model E4TN31: TM-score 0.89, RMSD 2.29 Å
- 6HD9 chain B against the predicted model E4TN31: TM-score 0.89, RMSD 2.29 Å
- 6HD9 chain B against the predicted model E4TN31: TM-score 0.89, RMSD 2.29 Å
Elsewhere
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