UniProt E3VWI3
Pentalenolactone synthase (E3VWI3)
Pentalenolactone synthase (UniProt E3VWI3), EC 1.14.19.8: 18 experimental structures and 1 predicted model on GenesisL1, 5 ligands bound, 15 pockets. Binding sites, druggability and experiment against prediction (TM-score) in…
- UniProt
- E3VWI3
- Protein
- Pentalenolactone synthase
- EC
- 1.14.19.8
- Experimental structures
- 18
- Predicted models
- 1
- Ligands
- 5
- Pockets
- 15 · 6 records with a druggable one
Structures
19 records of E3VWI3 in the MolNFT archive: 18 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5L1O | X-ray Structure of Cytochrome P450 PntM with Pentalenolactone F | x-ray diffraction | A | 7PF, HEM | — |
| 5L1O | X-ray structure of cytochrome P450 pntm with pentalenolactone F | x-ray diffraction | A | 7PF, HEM | — |
| 5L1P | X-ray Structure of Cytochrome P450 PntM with Pentalenolactone | x-ray diffraction | A | HEM, 7PT | 2 (best 0.86) |
| 5L1P | X-ray structure of cytochrome P450 pntm with pentalenolactone | x-ray diffraction | A | HEM, 7PT | — |
| 5L1Q | X-ray Structure of Cytochrome P450 PntM with Dihydropentalenolactone F | x-ray diffraction | A | HEM, 7DF | 2 (best 0.85) |
| 5L1Q | X-ray structure of cytochrome P450 pntm with dihydropentalenolactone F | x-ray diffraction | A | HEM, 7DF | — |
| 5L1R | X-ray Structure of the Substrate-free Cytochrome P450 PntM | x-ray diffraction | A | HEM, BCN | 2 (best 0.85) |
| 5L1R | X-ray structure of the substrate-free cytochrome P450 pntm | x-ray diffraction | A | HEM, BCN | — |
| 5L1S | X-ray Structure of F232L mutant of Cytochrome P450 PntM with pentalenolactone F | x-ray diffraction | A | 7PF, HEM | — |
| 5L1S | X-ray structure of F232L mutant of cytochrome P450 pntm with pentalenolactone F | x-ray diffraction | A | 7PF, HEM | — |
| 5L1T | X-ray Structure of M77S mutant of Cytochrome P450 PntM with pentalenolactone F | x-ray diffraction | A | 7PF, HEM | 3 (best 0.85) |
| 5L1T | X-ray structure of M77S mutant of cytochrome P450 pntm with pentalenolactone F | x-ray diffraction | A | 7PF, HEM | — |
| 5L1U | X-ray Structure of M81A mutant of Cytochrome P450 PntM with pentalenolactone F | x-ray diffraction | A | 7PF, HEM | — |
| 5L1U | X-ray structure of M81A mutant of cytochrome P450 pntm with pentalenolactone F | x-ray diffraction | A | 7PF, HEM | — |
| 5L1V | X-ray Structure of M81C mutant of Cytochrome P450 PntM with pentalenolactone F | x-ray diffraction | A | 7PF, HEM | 2 (best 0.85) |
| 5L1V | X-ray structure of M81C mutant of cytochrome P450 pntm with pentalenolactone F | x-ray diffraction | A | 7PF, HEM | — |
| 5L1W | X-ray Structure of 2-Mercaptoethanol modified M81C mutant of Cytochrome P450 PntM with… | x-ray diffraction | A | 7PF, HEM | — |
| 5L1W | X-ray structure of 2-mercaptoethanol modified M81C mutant of cytochrome P450 pntm with… | x-ray diffraction | A | 7PF, HEM | — |
| E3VWI3 | AlphaFold monomer V2.0 prediction for pentalenolactone synthase (E3VWI3) | predicted | A | — | 4 (best 0.86) |
Ligands
Experiment against prediction
- 5L1V chain A against the predicted model E3VWI3: TM-score 1.00, RMSD 0.16 Å
- 5L1V chain A against the predicted model E3VWI3: TM-score 1.00, RMSD 0.16 Å
- 5L1S chain A against the predicted model E3VWI3: TM-score 1.00, RMSD 0.16 Å
- 5L1S chain A against the predicted model E3VWI3: TM-score 1.00, RMSD 0.16 Å
- 5L1Q chain A against the predicted model E3VWI3: TM-score 1.00, RMSD 0.17 Å
- 5L1Q chain A against the predicted model E3VWI3: TM-score 1.00, RMSD 0.17 Å
- 5L1O chain A against the predicted model E3VWI3: TM-score 1.00, RMSD 0.18 Å
- 5L1O chain A against the predicted model E3VWI3: TM-score 1.00, RMSD 0.18 Å
- 5L1T chain A against the predicted model E3VWI3: TM-score 1.00, RMSD 0.18 Å
- 5L1T chain A against the predicted model E3VWI3: TM-score 1.00, RMSD 0.18 Å
Elsewhere
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