UniProt E2AXC7
BRCA1/BRCA2-containing complex subunit 3 (E2AXC7)
BRCA1/BRCA2-containing complex subunit 3 (UniProt E2AXC7): 6 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 45 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- E2AXC7
- Protein
- BRCA1/BRCA2-containing complex subunit 3
- Experimental structures
- 6
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 45 · 3 records with a druggable one
Structures
7 records of E2AXC7 in the MolNFT archive: 6 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5CW3 | Structure of CfBRCC36-CfKIAA0157 complex (Zn Edge) | x-ray diffraction | A, C | ZN | 15 (best 0.78) |
| 5CW3 | Structure of CFBRCC36-CFKIAA0157 complex (zn edge) | x-ray diffraction | A, C | — | — |
| 5CW4 | Structure of CfBRCC36-CfKIAA0157 complex (Selenium Edge) | x-ray diffraction | A, C | ZN | 17 (best 0.77) |
| 5CW4 | Structure of CFBRCC36-CFKIAA0157 complex (selenium edge) | x-ray diffraction | A, C | — | — |
| 5CW5 | Structure of CfBRCC36-CfKIAA0157 complex (QSQ mutant) | x-ray diffraction | A, C | — | 13 (best 0.76) |
| 5CW5 | Structure of CFBRCC36-CFKIAA0157 complex (qsq mutant) | x-ray diffraction | A, C | — | — |
| E2AXC7 | AlphaFold monomer V2.0 prediction for lys-63-specific deubiquitinase BRCC36 (E2AXC7) | predicted | A | — | — |
Ligands
- ZN · Zinc ion · in 2 records
Experiment against prediction
- 5CW3 chain C against the predicted model E2AXC7: TM-score 0.95, RMSD 1.44 Å
- 5CW3 chain C against the predicted model E2AXC7: TM-score 0.95, RMSD 1.44 Å
- 5CW4 chain C against the predicted model E2AXC7: TM-score 0.95, RMSD 1.48 Å
- 5CW4 chain C against the predicted model E2AXC7: TM-score 0.95, RMSD 1.48 Å
- 5CW4 chain A against the predicted model E2AXC7: TM-score 0.94, RMSD 1.63 Å
- 5CW4 chain A against the predicted model E2AXC7: TM-score 0.94, RMSD 1.63 Å
- 5CW3 chain A against the predicted model E2AXC7: TM-score 0.94, RMSD 1.65 Å
- 5CW3 chain A against the predicted model E2AXC7: TM-score 0.94, RMSD 1.65 Å
- 5CW5 chain A against the predicted model E2AXC7: TM-score 0.93, RMSD 1.73 Å
- 5CW5 chain A against the predicted model E2AXC7: TM-score 0.93, RMSD 1.73 Å
Elsewhere
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