UniProt E2AB17
Protein FAM175B (E2AB17)
Protein FAM175B (UniProt E2AB17): 6 experimental structures and 1 predicted model on GenesisL1, 36 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- E2AB17
- Protein
- Protein FAM175B
- Experimental structures
- 6
- Predicted models
- 1
- Pockets
- 36 · 3 records with a druggable one
Structures
7 records of E2AB17 in the MolNFT archive: 6 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5CW3 | Structure of CfBRCC36-CfKIAA0157 complex (Zn Edge) | x-ray diffraction | B, D | — | 11 (best 0.78) |
| 5CW3 | Structure of CFBRCC36-CFKIAA0157 complex (zn edge) | x-ray diffraction | B, D | — | — |
| 5CW4 | Structure of CfBRCC36-CfKIAA0157 complex (Selenium Edge) | x-ray diffraction | B, D | — | 15 (best 0.77) |
| 5CW4 | Structure of CFBRCC36-CFKIAA0157 complex (selenium edge) | x-ray diffraction | B, D | — | — |
| 5CW5 | Structure of CfBRCC36-CfKIAA0157 complex (QSQ mutant) | x-ray diffraction | B, D | — | 10 (best 0.76) |
| 5CW5 | Structure of CFBRCC36-CFKIAA0157 complex (qsq mutant) | x-ray diffraction | B, D | — | — |
| E2AB17 | AlphaFold monomer V2.0 prediction for brisc complex subunit FAM175B (E2AB17) | predicted | A | — | — |
Experiment against prediction
- 5CW5 chain B against the predicted model E2AB17: TM-score 0.99, RMSD 0.55 Å
- 5CW5 chain B against the predicted model E2AB17: TM-score 0.99, RMSD 0.55 Å
- 5CW3 chain D against the predicted model E2AB17: TM-score 0.98, RMSD 0.80 Å
- 5CW3 chain D against the predicted model E2AB17: TM-score 0.98, RMSD 0.80 Å
- 5CW5 chain D against the predicted model E2AB17: TM-score 0.98, RMSD 0.86 Å
- 5CW5 chain D against the predicted model E2AB17: TM-score 0.98, RMSD 0.86 Å
- 5CW3 chain B against the predicted model E2AB17: TM-score 0.98, RMSD 1.04 Å
- 5CW3 chain B against the predicted model E2AB17: TM-score 0.98, RMSD 1.04 Å
- 5CW4 chain B against the predicted model E2AB17: TM-score 0.98, RMSD 1.09 Å
- 5CW4 chain B against the predicted model E2AB17: TM-score 0.98, RMSD 1.09 Å
Elsewhere
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