UniProt E1C9K5
DNA polymerase I (E1C9K5)
DNA polymerase I (UniProt E1C9K5), EC 2.7.7.7: 52 experimental structures on GenesisL1, 6 ligands bound, 94 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- E1C9K5
- Protein
- DNA polymerase I
- EC
- 2.7.7.7
- Experimental structures
- 52
- Predicted models
- 0
- Ligands
- 6
- Pockets
- 94 · 11 records with a druggable one
Structures
52 records of E1C9K5 in the MolNFT archive: 52 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2XY5 | Crystal structure of an artificial salen-copper basepair in complex with fragment DNA polymerase I… | x-ray diffraction | A | — | — |
| 2XY5 | Crystal structure of an artificial salen-copper basepair in complex with fragment DNA polymerase I… | x-ray diffraction | A | — | — |
| 2XY6 | Crystal structure of a salicylic aldehyde basepair in complex with fragment DNA polymerase I from… | x-ray diffraction | A | — | — |
| 2XY6 | Crystal structure of a salicylic aldehyde basepair in complex with fragment DNA polymerase I from… | x-ray diffraction | A | — | — |
| 2XY7 | Crystal structure of a salicylic aldehyde base in the pre-insertion site of fragment DNA polymerase… | x-ray diffraction | A | — | — |
| 2XY7 | Crystal structure of a salicylic aldehyde base in the pre-insertion site of fragment DNA polymerase… | x-ray diffraction | A | — | — |
| 4B9L | Structure of the high fidelity DNA polymerase I with the oxidative formamidopyrimidine-dA DNA… | x-ray diffraction | A | — | — |
| 4B9L | Structure of the high fidelity DNA polymerase I with the oxidative formamidopyrimidine-da DNA… | x-ray diffraction | A | — | — |
| 4B9M | Structure of the high fidelity DNA polymerase I with an oxidative formamidopyrimidine-dA DNA lesion… | x-ray diffraction | A | — | — |
| 4B9M | Structure of the high fidelity DNA polymerase I with an oxidative formamidopyrimidine-da DNA lesion… | x-ray diffraction | A | — | — |
| 4B9N | Structure of the high fidelity DNA polymerase I correctly bypassing the oxidative… | x-ray diffraction | A | — | — |
| 4B9N | Structure of the high fidelity DNA polymerase I correctly bypassing the oxidative… | x-ray diffraction | A | — | — |
| 4B9S | Structure of the high fidelity DNA polymerase I with an oxidative formamidopyrimidine-dG DNA lesion… | x-ray diffraction | A | — | — |
| 4B9S | Structure of the high fidelity DNA polymerase I with an oxidative formamidopyrimidine-dg DNA lesion… | x-ray diffraction | A | — | — |
| 4B9T | Structure of the high fidelity DNA polymerase I with an oxidative formamidopyrimidine-dG DNA lesion… | x-ray diffraction | A | — | — |
| 4B9T | Structure of the high fidelity DNA polymerase I with an oxidative formamidopyrimidine-dg DNA lesion… | x-ray diffraction | A | — | — |
| 4B9U | Structure of the high fidelity DNA polymerase I with an oxidative formamidopyrimidine-dG DNA lesion… | x-ray diffraction | A | — | — |
| 4B9U | Structure of the high fidelity DNA polymerase I with an oxidative formamidopyrimidine-dg DNA lesion… | x-ray diffraction | A | — | — |
| 4B9V | Structure of the high fidelity DNA polymerase I with extending from an oxidative… | x-ray diffraction | A | — | — |
| 4B9V | Structure of the high fidelity DNA polymerase I with extending from an oxidative… | x-ray diffraction | A | — | — |
| 4UQG | A new bio-isosteric base pair based on reversible bonding | x-ray diffraction | A | — | — |
| 4UQG | A new bio-isosteric base pair based on reversible bonding | x-ray diffraction | A | — | — |
| 4YFU | Crystal structure of open Bacillus fragment DNA polymerase bound to DNA and dTTP | x-ray diffraction | A, D | — | — |
| 4YFU | Crystal structure of open bacillus fragment DNA polymerase bound to DNA and dttp | x-ray diffraction | A, D | — | — |
| 6DSU | Bst DNA polymerase I pre-insertion complex structure | x-ray diffraction | A | MG, SO4, DZ4 | — |
| 6DSU | Bst DNA polymerase I pre-insertion complex structure | x-ray diffraction | A | MG, SO4, DZ4 | — |
| 6DSV | Bst DNA polymerase I post-chemistry (n+2) structure | x-ray diffraction | A | MG, SO4 | 9 (best 0.79) |
| 6DSV | Bst DNA polymerase I post-chemistry (N+2) structure | x-ray diffraction | A | MG, SO4 | — |
| 6DSW | Bst DNA polymerase I pre-chemistry (n) structure | x-ray diffraction | A | SO4, MG | 10 (best 0.72) |
| 6DSW | Bst DNA polymerase I pre-chemistry (N) structure | x-ray diffraction | A | SO4, MG | — |
| 6DSX | Bst DNA polymerase I post-chemistry (n+1 with dATP soak) structure | x-ray diffraction | A | SO4, MG | 8 (best 0.71) |
| 6DSX | Bst DNA polymerase I post-chemistry (N+1 with datp soak) structure | x-ray diffraction | A | SO4, MG | — |
| 6DSY | Bst DNA polymerase I post-chemistry (n+1) structure | x-ray diffraction | A | MG, SO4 | 11 (best 0.75) |
| 6DSY | Bst DNA polymerase I post-chemistry (N+1) structure | x-ray diffraction | A | MG, SO4 | — |
| 6MU4 | Bst DNA polymerase I FANA/DNA binary complex | x-ray diffraction | A | SO4, MG | — |
| 6MU4 | Bst DNA polymerase I FANA/DNA binary complex | x-ray diffraction | A | SO4, MG | — |
| 6MU5 | Bst DNA polymerase I TNA/DNA binary complex | x-ray diffraction | A | SO4 | 6 (best 0.72) |
| 6MU5 | Bst DNA polymerase I TNA/DNA binary complex | x-ray diffraction | A | TFT, SO4 | — |
| 7K5O | Bst DNA polymerase I time-resolved structure, 1 min post dATP addition | x-ray diffraction | A | SO4 | 10 (best 0.70) |
| 7K5O | Bst DNA polymerase I time-resolved structure, 1 min post datp addition | x-ray diffraction | A | SO4 | — |
| 7K5P | Bst DNA polymerase I time-resolved structure, 4 min post dATP addition | x-ray diffraction | A | SO4 | 9 (best 0.72) |
| 7K5P | Bst DNA polymerase I time-resolved structure, 4 min post datp addition | x-ray diffraction | A | SO4 | — |
| 7K5Q | Bst DNA polymerase I time-resolved structure, 8 min post dATP addition | x-ray diffraction | A | SO4, DTP | 8 (best 0.74) |
| 7K5Q | Bst DNA polymerase I time-resolved structure, 8 min post datp addition | x-ray diffraction | A | SO4, DTP | — |
| 7K5R | Bst DNA polymerase I time-resolved structure, 120 min post dATP addition | x-ray diffraction | A | SO4 | 6 (best 0.72) |
| 7K5R | Bst DNA polymerase I time-resolved structure, 120 min post datp addition | x-ray diffraction | A | SO4 | — |
| 7K5S | Bst DNA polymerase I time-resolved structure, 4 hr post dATP and dCTP addition | x-ray diffraction | A | SO4 | — |
| 7K5S | Bst DNA polymerase I time-resolved structure, 4 hr post datp and dctp addition | x-ray diffraction | A | SO4 | — |
| 7K5T | Bst DNA polymerase I time-resolved structure, 25.5 hr post dATP and dCTP addition | x-ray diffraction | A | SO4, DCP | 8 (best 0.71) |
| 7K5T | Bst DNA polymerase I time-resolved structure, 25.5 hr post datp and dctp addition | x-ray diffraction | A | SO4, DCP | — |
| 7K5U | Bst DNA polymerase I time-resolved structure, 48 hr post dATP and dCTP addition | x-ray diffraction | A | SO4 | 9 (best 0.71) |
| 7K5U | Bst DNA polymerase I time-resolved structure, 48 hr post datp and dctp addition | x-ray diffraction | A | SO4 | — |
Ligands
- SO4 · Sulfate ion · in 28 records
- MG · Magnesium ion · in 12 records
- DCP · 2'-deoxycytidine-5'-triphosphate · in 2 records
- DTP · 2'-deoxyadenosine 5'-triphosphate · in 2 records
- DZ4 · 2'-deoxy-5'-O-[(R)-hydroxy{[(r)-hydroxy(phosphonooxy) phosphoryl]amino}phosphoryl]adenosine · in 2 records
- TFT · (L)-alpha-threofuranosyl-thymine-3'-monophosphate · in 1 record
Elsewhere
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