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UniProt D3XFN7

Pol protein (D3XFN7)

Pol protein (UniProt D3XFN7): 9 experimental structures on GenesisL1, 5 ligands bound, 60 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.

UniProt
D3XFN7
Protein
Pol protein
Experimental structures
9
Predicted models
0
Ligands
5
Pockets
60 · 3 records with a druggable one

Structures

9 records of D3XFN7 in the MolNFT archive: 9 experimental, 0 predicted.

EntryTitleMethodChainsLigandsPockets
5XN0HIV-1 reverse transcriptase Q151M:DNA binary complexx-ray diffractionA, B, C, DGLC, FRU20 (best 0.84)
5XN0HIV-1 reverse transcriptase Q151M:DNA binary complexx-ray diffractionA, B, C, DGLC, FRU—
5XN1HIV-1 reverse transcriptase Q151M:DNA:entecavir-triphosphate ternary complexx-ray diffractionA, B, C, DGLC, FRU, ET9, MG20 (best 0.82)
5XN1HIV-1 reverse transcriptase Q151M:DNA:ENTECAVIR-triphosphate ternary complexx-ray diffractionA, B, C, DGLC, FRU, ET9, MG—
5XN2HIV-1 reverse transcriptase Q151M:DNA:dGTP ternary complexx-ray diffractionA, B, C, DGLC, FRU, MG, DGT20 (best 0.86)
5XN2HIV-1 reverse transcriptase Q151M:DNA:DGTP ternary complexx-ray diffractionA, B, C, DGLC, FRU, MG, DGT—
6IK9HIV-1 reverse transcriptase with Q151M/G112S/D113A/Y115F/F116Y/F160L/I159L:DNA:DGTP ternary complexx-ray diffractionA, CDGT, MG—
6IKAHIV-1 reverse transcriptase with Q151M/G112S/D113A/Y115F/F116Y/F160L/I159L:DNA:entecavir-triphosphat…x-ray diffractionA, CET9, MG—
6IKAHIV-1 reverse transcriptase with Q151M/G112S/D113A/Y115F/F116Y/F160L/I159L:DNA:ENTECAVIR-triphosphat…x-ray diffractionA, CET9, MG—

Ligands

  • MG · Magnesium ion · in 7 records
  • FRU · beta-D-fructofuranose · in 6 records
  • GLC · alpha-D-glucopyranose · in 6 records
  • ET9 · [[(1R,3S,5S)-3-(2-azanyl-6-oxidanylidene-3H-purin-9-yl)-2-methylidene-5-oxidanyl-cyclopentyl]methoxy-oxidanyl-phosphory l] phosphono hydrogen phosphate · in 4 records
  • DGT · 2'-deoxyguanosine-5'-triphosphate · in 3 records

Elsewhere

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