UniProt D3XFN5
Pol protein (Fragment) (D3XFN5)
Pol protein (Fragment) (UniProt D3XFN5), EC 2.7.7.49, 3.1.26.13: 16 experimental structures on GenesisL1, 6 ligands bound, 80 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- D3XFN5
- Protein
- Pol protein (Fragment)
- EC
- 2.7.7.49, 3.1.26.13
- Experimental structures
- 16
- Predicted models
- 0
- Ligands
- 6
- Pockets
- 80 · 5 records with a druggable one
Structures
16 records of D3XFN5 in the MolNFT archive: 16 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6KDJ | HIV-1 reverse transcriptase with Q151M/Y115F/F116Y:DNA:lamivudine 5'-triphosphate ternary complex | x-ray diffraction | A, C | 1RZ, MG | — |
| 6KDJ | HIV-1 reverse transcriptase with Q151M/Y115F/F116Y:DNA:LAMIVUDINE 5'- triphosphate ternary complex | x-ray diffraction | A, C | 1RZ, MG | — |
| 6KDK | HIV-1 reverse transcriptase with Q151M/Y115F/F116Y:DNA:dCTP ternary complex | x-ray diffraction | A, C | DCP, MG | — |
| 6KDK | HIV-1 reverse transcriptase with Q151M/Y115F/F116Y:DNA:DCTP ternary complex | x-ray diffraction | A, C | DCP, MG | — |
| 6KDM | HIV-1 reverse transcriptase with Q151M/Y115F/F116Y:DNA:entecavir 5'-triphosphate ternary complex | x-ray diffraction | A, C | MG, ET9 | — |
| 6KDM | HIV-1 reverse transcriptase with Q151M/Y115F/F116Y:DNA:ENTECAVIR 5'- triphosphate ternary complex | x-ray diffraction | A, C | MG, ET9 | — |
| 6KDN | HIV-1 reverse transcriptase with Q151M/Y115F/F116Y:DNA:dGTP ternary complex | x-ray diffraction | A, C | MG, DGT | — |
| 6KDN | HIV-1 reverse transcriptase with Q151M/Y115F/F116Y:DNA:DGTP ternary complex | x-ray diffraction | A, C | MG, DGT | — |
| 6KDO | HIV-1 reverse transcriptase with Q151M/Y115F/F116Y/M184V/F160M:DNA:LAMIVUDINE 5'-triphosphate… | x-ray diffraction | A, C | 1RZ | — |
| 7DBM | HIV-1 reverse transcriptase mutant Q151M/Y115F/F116Y/M184V:DNA:DGTP ternary complex | x-ray diffraction | A, C | DGT, MG | — |
| 7DBN | HIV-1 reverse transcriptase mutant Q151M/Y115F/F116Y/M184V/F160M:DNA:dCTP ternary complex | x-ray diffraction | A, C | DCP, MG | 16 (best 0.83) |
| 7DBN | HIV-1 reverse transcriptase mutant Q151M/Y115F/F116Y/M184V/F160M:DNA:DCTP ternary complex | x-ray diffraction | A, C | DCP, MG | — |
| 8X1Z | HIV-1 reverse transcriptase mutant Q151M/Y115F/F116Y:DNA:E-CFCP-TP ternary complex | x-ray diffraction | A, C | MG, XTE | 16 (best 0.85) |
| 8X20 | HIV-1 reverse transcriptase mutant Q151M/Y115F/F116Y/L74V:DNA:E-CFCP-TP ternary complex | x-ray diffraction | A, C | XTE, MG | 16 (best 0.86) |
| 8X21 | HIV-1 reverse transcriptase mutant Q151M/Y115F/F116Y/L74V:DNA:ETV-TP ternary complex | x-ray diffraction | A, C | ET9, MG | 16 (best 0.83) |
| 8X22 | HIV-1 reverse transcriptase mutant Q151M/Y115F/F116Y/L74V:DNA:dGTP ternary complex | x-ray diffraction | A, C | DGT, MG | 16 (best 0.83) |
Ligands
- MG · Magnesium ion · in 15 records
- DCP · 2'-deoxycytidine-5'-triphosphate · in 4 records
- DGT · 2'-deoxyguanosine-5'-triphosphate · in 4 records
- 1RZ · Lamivudine Triphosphate · in 3 records
- ET9 · [[(1R,3S,5S)-3-(2-azanyl-6-oxidanylidene-3H-purin-9-yl)-2-methylidene-5-oxidanyl-cyclopentyl]methoxy-oxidanyl-phosphory l] phosphono hydrogen phosphate · in 3 records
- XTE · E-CFCP-triphosphate · in 2 records
Elsewhere
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