UniProt D3DSX2
Fibroblast growth factor receptor 1 (fms-related tyrosine kinase 2, pfeiffer syndrome), isoform CRA_B (D3DSX2)
Fibroblast growth factor receptor 1 (fms-related tyrosine kinase 2, pfeiffer syndrome), isoform CRA_B (UniProt D3DSX2): 8 experimental structures on GenesisL1, 2 ligands bound, 4 pockets. Binding sites, pockets, druggability and…
- UniProt
- D3DSX2
- Protein
- Fibroblast growth factor receptor 1 (fms-related tyrosine kinase 2, pfeiffer…
- Experimental structures
- 8
- Predicted models
- 0
- Ligands
- 2
- Pockets
- 4 · 1 record with a druggable one
Structures
8 records of D3DSX2 in the MolNFT archive: 8 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4V01 | FGFR1 in complex with ponatinib (co-crystallisation). | x-ray diffraction | A, B | — | — |
| 4V01 | FGFR1 in complex with ponatinib (co-crystallisation). | x-ray diffraction | A, B | — | — |
| 4V04 | FGFR1 in complex with ponatinib. | x-ray diffraction | A, B | — | — |
| 4V04 | FGFR1 in complex with ponatinib. | x-ray diffraction | A, B | — | — |
| 4V05 | FGFR1 in complex with AZD4547. | x-ray diffraction | A, B | — | — |
| 4V05 | FGFR1 in complex with AZD4547. | x-ray diffraction | A, B | — | — |
| 5A46 | FGFR1 in complex with dovitinib | x-ray diffraction | A, B | 38O, SO4 | 4 (best 0.73) |
| 5A46 | FGFR1 in complex with dovitinib | x-ray diffraction | A, B | — | — |
Ligands
Elsewhere
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