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UniProt D0ZVG2

E3 ubiquitin-protein ligase SSPH1 (D0ZVG2)

E3 ubiquitin-protein ligase SSPH1 (UniProt D0ZVG2): 4 experimental structures and 1 predicted model on GenesisL1, 6 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.

UniProt
D0ZVG2
Protein
E3 ubiquitin-protein ligase SSPH1
Experimental structures
4
Predicted models
1
Pockets
6 · 1 record with a druggable one

Structures

5 records of D0ZVG2 in the MolNFT archive: 4 experimental, 1 predicted.

EntryTitleMethodChainsLigandsPockets
4NKGCrystal structure of SspH1 LRR domain in complex PKN1 HR1b domainx-ray diffractionA, C——
4NKGCrystal structure of SSPH1 lrr domain in complex PKN1 HR1B domainx-ray diffractionA, C——
4NKHCrystal structure of SspH1 LRR domainx-ray diffractionA, B, C, D, E, F——
4NKHCrystal structure of SSPH1 lrr domainx-ray diffractionA, B, C, D, E, F——
D0ZVG2AlphaFold monomer V2.0 prediction for E3 ubiquitin-protein ligase SSPH1 (D0ZVG2)predictedA—6 (best 0.58)

Experiment against prediction

Elsewhere

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