UniProt C4B644
Vitamin D(3) 25-hydroxylase (C4B644)
Vitamin D(3) 25-hydroxylase (UniProt C4B644), EC 1.14.15.15: 15 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 17 pockets. Binding sites, druggability and experiment against prediction (TM-score) in…
- UniProt
- C4B644
- Protein
- Vitamin D(3) 25-hydroxylase
- EC
- 1.14.15.15
- Experimental structures
- 15
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 17 · 1 record with a druggable one
Structures
16 records of C4B644 in the MolNFT archive: 15 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3A4G | Structure of cytochrome P450 vdh from Pseudonocardia autotrophica (trigonal crystal form) | x-ray diffraction | A | — | — |
| 3A4G | Structure of cytochrome P450 vdh from pseudonocardia autotrophica (trigonal crystal form) | x-ray diffraction | A | — | — |
| 3A4H | Structure of cytochrome P450 vdh from Pseudonocardia autotrophica (orthorhombic crystal form) | x-ray diffraction | A | — | — |
| 3A4H | Structure of cytochrome P450 vdh from pseudonocardia autotrophica (orthorhombic crystal form) | x-ray diffraction | A | — | — |
| 3A4Z | Structure of cytochrome P450 Vdh mutant (Vdh-K1) obtained by directed evolution | x-ray diffraction | A, B, C, D, E | — | — |
| 3A4Z | Structure of cytochrome P450 vdh mutant (vdh-K1) obtained by directed evolution | x-ray diffraction | A, B, C, D, E | — | — |
| 3A50 | Structure of cytochrome P450 Vdh mutant (Vdh-K1) obtained by directed evolution with bound vitamin… | x-ray diffraction | A, B, C, D, E | — | — |
| 3A50 | Structure of cytochrome P450 vdh mutant (vdh-K1) obtained by directed evolution with bound vitamin… | x-ray diffraction | A, B, C, D, E | — | — |
| 3A51 | Structure of cytochrome P450 Vdh mutant (Vdh-K1) obtained by directed evolution with bound… | x-ray diffraction | A, B, C, D, E | — | — |
| 3A51 | Structure of cytochrome P450 vdh mutant (vdh-K1) obtained by directed evolution with bound… | x-ray diffraction | A, B, C, D, E | — | — |
| 3VRM | Structure of cytochrome P450 Vdh mutant T107A with bound vitamin D3 | x-ray diffraction | A | — | — |
| 3VRM | Structure of cytochrome P450 vdh mutant T107A with bound vitamin D3 | x-ray diffraction | A | — | — |
| 5GNL | Cytochrome P450 vdh (CYP107BR1) F106V mutant | x-ray diffraction | A | — | — |
| 5GNM | Cytochrome P450 Vdh (CYP107BR1) L348M mutant | x-ray diffraction | A, B, C, D | HEM | 17 (best 0.82) |
| 5GNM | Cytochrome P450 vdh (CYP107BR1) L348M mutant | x-ray diffraction | A, B, C, D | — | — |
| C4B644 | AlphaFold monomer V2.0 prediction for vitamin D(3) 25-hydroxylase (C4B644) | predicted | A | — | — |
Ligands
- HEM · Protoporphyrin IX containing Fe · in 1 record
Experiment against prediction
- 3A51 chain A against the predicted model C4B644: TM-score 1.00, RMSD 0.38 Å
- 3A51 chain A against the predicted model C4B644: TM-score 1.00, RMSD 0.38 Å
- 3A4Z chain A against the predicted model C4B644: TM-score 1.00, RMSD 0.38 Å
- 3A4Z chain A against the predicted model C4B644: TM-score 1.00, RMSD 0.38 Å
- 3A50 chain A against the predicted model C4B644: TM-score 1.00, RMSD 0.39 Å
- 3A50 chain A against the predicted model C4B644: TM-score 1.00, RMSD 0.39 Å
- 3A50 chain C against the predicted model C4B644: TM-score 1.00, RMSD 0.41 Å
- 3A50 chain C against the predicted model C4B644: TM-score 1.00, RMSD 0.41 Å
- 3A50 chain B against the predicted model C4B644: TM-score 1.00, RMSD 0.42 Å
- 3A50 chain B against the predicted model C4B644: TM-score 1.00, RMSD 0.42 Å
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.