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UniProt C3W5X5

Polymerase basic protein 2 (C3W5X5)

Polymerase basic protein 2 (UniProt C3W5X5): 5 experimental structures on GenesisL1, 3 ligands bound, 1 pocket. Binding sites, pockets, druggability and 3D structures in GL1X.

UniProt
C3W5X5
Protein
Polymerase basic protein 2
Experimental structures
5
Predicted models
0
Ligands
3
Pockets
1 · 0 records with a druggable one

Structures

5 records of C3W5X5 in the MolNFT archive: 5 experimental, 0 predicted.

EntryTitleMethodChainsLigandsPockets
7AS0Influenza a PB2 in complex with vx-787x-ray diffractionA21G, BR—
7AS1Influenza a PB2 (F404Y mutation) in complex with vx-787x-ray diffractionA21G, CL—
7AS2Influenza a PB2 (M431 mutation) in complex with vx-787x-ray diffractionA21G—
7AS3Influenza A PB2 (H357N mutation) in complex with VX-787x-ray diffractionA21G1 (best 0.43)
7AS3Influenza a PB2 (H357N mutation) in complex with vx-787x-ray diffractionA21G—

Ligands

  • 21G · (2S,3S)-3-[[5-fluoranyl-2-(5-fluoranyl-1H-pyrrolo[2,3-b]pyridin-3-yl)pyrimidin-4-yl]amino]bicyclo[2.2.2]octane-2-carboxylic acid · in 5 records
  • BR · Bromide ion · in 1 record
  • CL · Chloride ion · in 1 record

Elsewhere

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