UniProt C3V2B5

Corticotropin-releasing factor receptor 1,Lysozyme,Corticotropin-releasing factor receptor 1 (C3V2B5)

Corticotropin-releasing factor receptor 1,Lysozyme,Corticotropin-releasing factor receptor 1 (UniProt C3V2B5), EC 3.2.1.17: 2 experimental structures on GenesisL1, 3 ligands bound, 14 pockets. Binding sites, pockets, druggability…

UniProt: C3V2B5
Protein: Corticotropin-releasing factor receptor 1,Lysozyme,Corticotropin-releasing…
EC: 3.2.1.17
Experimental structures: 2
Predicted models: 0
Ligands: 3
Pockets: 14 · 1 record with a druggable one

Structures

2 records of C3V2B5 in the MolNFT archive: 2 experimental, 0 predicted.

Entry	Title	Method	Chains	Ligands	Pockets
4Z9G	Crystal structure of human corticotropin-releasing factor receptor 1 (CRF1R) in complex with the…	x-ray diffraction	A, B, C	OLA, 1Q5, SO4	14 (best 0.81)
4Z9G	Crystal structure of human corticotropin-releasing factor receptor 1 (CRF1R) in complex with the…	x-ray diffraction	A, B, C	—	—

Ligands

1Q5 · 3,6-dimethyl-N-(pentan-3-yl)-2-(2,4,6-trimethylphenoxy)pyridin-4-amine · in 1 record
OLA · Oleic acid · in 1 record
SO4 · Sulfate ion · in 1 record

Experiment against prediction

4Z9G chain A against the predicted model P34998: TM-score 0.54, RMSD 3.25 Å
4Z9G chain A against the predicted model P34998: TM-score 0.54, RMSD 3.25 Å
4Z9G chain B against the predicted model P34998: TM-score 0.53, RMSD 3.39 Å
4Z9G chain B against the predicted model P34998: TM-score 0.53, RMSD 3.39 Å
4Z9G chain C against the predicted model P34998: TM-score 0.51, RMSD 3.58 Å
4Z9G chain C against the predicted model P34998: TM-score 0.51, RMSD 3.58 Å

Elsewhere

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