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UniProt C3T0H0

Efflux pump membrane transporter (C3T0H0)

Efflux pump membrane transporter (UniProt C3T0H0): 4 experimental structures on GenesisL1, 1 ligand bound, 80 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.

UniProt
C3T0H0
Protein
Efflux pump membrane transporter
Experimental structures
4
Predicted models
0
Ligands
1
Pockets
80 · 4 records with a druggable one

Structures

4 records of C3T0H0 in the MolNFT archive: 4 experimental, 0 predicted.

EntryTitleMethodChainsLigandsPockets
8F3ETrimer of aminoglycoside efflux pump AcrDelectron microscopyA, B, C—20 (best 0.89)
8F4NDimer of aminoglycoside efflux pump AcrDelectron microscopyB, A—20 (best 0.84)
8F4RGentamicin bound aminoglycoside efflux pump AcrDelectron microscopyA, B, CLLL20 (best 0.87)
8F56Dimer of aminoglycoside efflux pump AcrD treated with gentamicinelectron microscopyA, B—20 (best 0.84)

Ligands

  • LLL · (2R,3R,4R,5R)-2-((1S,2S,3R,4S,6R)-4,6-diamino-3-((2R, 3R,6S)-3-amino-6-(aminomethyl)-tetrahydro-2H-pyran-2-yloxy)-2-hydroxycyclohexyloxy)-5-methyl-4-(methylamino)-tetrahydro-2H-pyran-3,5-diol · in 1 record

Elsewhere

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