UniProt B8NJH3
O-methyltransferase lepI (B8NJH3)
O-methyltransferase lepI (UniProt B8NJH3), EC 2.1.1.-: 20 experimental structures on GenesisL1, 8 ligands bound, 18 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- B8NJH3
- Protein
- O-methyltransferase lepI
- EC
- 2.1.1.-
- Experimental structures
- 20
- Predicted models
- 0
- Ligands
- 8
- Pockets
- 18 · 3 records with a druggable one
Structures
20 records of B8NJH3 in the MolNFT archive: 20 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5ZZD | Crystal structure of a protein from Aspergillus flavus | x-ray diffraction | A, B | SAM | 5 (best 0.85) |
| 5ZZD | Crystal structure of a protein from aspergillus flavus | x-ray diffraction | A, B | — | — |
| 6INW | A Pericyclic Reaction enzyme | x-ray diffraction | A, B | — | — |
| 6INW | A pericyclic reaction enzyme | x-ray diffraction | A, B | — | — |
| 6IV7 | The crystal structure of a SAM-dependent enzyme from aspergillus flavus | x-ray diffraction | A, B | SAH | 6 (best 0.87) |
| 6IV7 | The crystal structure of a SAM-dependent enzyme from aspergillus flavus | x-ray diffraction | A, B | — | — |
| 6IX3 | The structure of LepI complex with SAM | x-ray diffraction | A, B | CL | — |
| 6IX3 | The structure of lepi complex with SAM | x-ray diffraction | A, B | CL | — |
| 6IX5 | The structure of LepI complex with SAM and its substrate analogue | x-ray diffraction | A, B | B0L, CL, NA | — |
| 6IX5 | The structure of lepi complex with SAM and its substrate analogue | x-ray diffraction | A, B | B0L, CL, NA | — |
| 6IX7 | The structure of LepI C52A in complex with SAH and substrate analogue | x-ray diffraction | A, B | B0L, CL | — |
| 6IX7 | The structure of lepi C52A in complex with sah and substrate analogue | x-ray diffraction | A, B | B0L, CL | — |
| 6IX8 | The structure of LepI C52A in complex with SAM and its substrate analogue | x-ray diffraction | A, B | CL, NA, B3O | — |
| 6IX8 | The structure of lepi C52A in complex with SAM and its substrate analogue | x-ray diffraction | A, B | CL, NA, B3O | — |
| 6IX9 | The structure of LepI C52A in complex with SAM and leporin C | x-ray diffraction | A, B | NA, B0O, CL | — |
| 6IX9 | The structure of lepi C52A in complex with SAM and leporin C | x-ray diffraction | A, B | NA, B0O, CL | — |
| 6J1O | Crystal structure of a SAM-dependent methyltransferase lepi from aspergillus flavus | x-ray diffraction | A, B | MTA | — |
| 6J46 | LepI-SAH complex structure | x-ray diffraction | A, B | SAH | 7 (best 0.86) |
| 6J46 | Lepi-sah complex structure | x-ray diffraction | A, B | — | — |
| B8NJH3 | AlphaFold monomer V2.0 prediction for O-methyltransferase lepi (B8NJH3) | — | — | — |
Ligands
- CL · Chloride ion · in 10 records
- NA · Sodium ion · in 6 records
- B0L · 4-hydroxy-3-[(2S,6E,8E)-2-methyldeca-6,8-dienoyl]-5-phenylpyridin-2(1H)-one · in 4 records
- B0O · (6R,6aS,10S,10aR)-10-methyl-4-phenyl-6-[(1E)-prop-1-en-1-yl]-2,6,6a,7,8,9,10,10a-octahydro-1H-[2]benzopyrano[4,3-c]pyridin-1-one · in 2 records
- B3O · (1r,2r,4as,8s,8ar)-2,8-dimethyl-5'-phenyl-4A,5,6,7,8, 8A-hexahydro-2H,2'H-spiro[naphthalene-1,3'-pyridine]-2',4'(1'H)-dione · in 2 records
- SAH · S-adenosyl-L-homocysteine · in 2 records
- MTA · 5'-deoxy-5'-methylthioadenosine · in 1 record
- SAM · S-adenosylmethionine · in 1 record
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.