UniProt B7ZSK1
N-methyl-D-aspartate receptor subunit NR2A (B7ZSK1)
N-methyl-D-aspartate receptor subunit NR2A (UniProt B7ZSK1): 4 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 27 pockets. Binding sites, druggability and experiment against prediction (TM-score) in…
- UniProt
- B7ZSK1
- Protein
- N-methyl-D-aspartate receptor subunit NR2A
- Experimental structures
- 4
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 27 · 3 records with a druggable one
Structures
5 records of B7ZSK1 in the MolNFT archive: 4 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5UOW | Triheteromeric NMDA receptor GluN1/GluN2A/GluN2B in complex with glycine, glutamate, MK-801 and a… | electron microscopy | B | GLU, BMK | 8 (best 0.90) |
| 5UOW | Triheteromeric NMDA receptor GLUN1/GLUN2A/GLUN2B in complex with glycine, glutamate, mk-801 and a… | electron microscopy | B | BMK | — |
| 5UP2 | Triheteromeric NMDA receptor GluN1/GluN2A/GluN2B in complex with glycine, glutamate, Ro 25-6981… | electron microscopy | B | — | 8 (best 0.89) |
| 5UP2 | Triheteromeric NMDA receptor GLUN1/GLUN2A/GLUN2B in complex with glycine, glutamate, ro 25-6981… | electron microscopy | B | — | — |
| B7ZSK1 | AlphaFold monomer V2.0 prediction for glutamate receptor ionotropic, NMDA 2A (B7ZSK1) | predicted | A | — | 11 (best 0.72) |
Ligands
Experiment against prediction
- 5UOW chain B against the predicted model B7ZSK1: TM-score 0.94, RMSD 2.54 Å
- 5UOW chain B against the predicted model B7ZSK1: TM-score 0.94, RMSD 2.54 Å
- 5UP2 chain B against the predicted model B7ZSK1: TM-score 0.93, RMSD 2.78 Å
- 5UP2 chain B against the predicted model B7ZSK1: TM-score 0.93, RMSD 2.78 Å
Elsewhere
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