UniProt B7MLA0
Enolase (B7MLA0)
Enolase (UniProt B7MLA0), EC 4.2.1.11: 8 experimental structures and 1 predicted model on GenesisL1, 6 ligands bound, 140 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- B7MLA0
- Protein
- Enolase
- EC
- 4.2.1.11
- Experimental structures
- 8
- Predicted models
- 1
- Ligands
- 6
- Pockets
- 140 · 8 records with a druggable one
Structures
9 records of B7MLA0 in the MolNFT archive: 8 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6BFY | Crystal structure of enolase from Escherichia coli with bound 2-phosphoglycerate substrate | x-ray diffraction | A, B, C, F, D, E | 2PG, MG, SO4 | 17 (best 0.83) |
| 6BFY | Crystal structure of enolase from escherichia COLI with bound 2- phosphoglycerate substrate | x-ray diffraction | A, B, C, F, D, E | 2PG, MG, SO4 | 17 (best 0.83) |
| 6BFZ | Crystal structure of enolase from E. coli with a mixture of apo form, substrate, and product form | x-ray diffraction | A, B, E, F, D, C | MG, SO4, PEP, 2PG | 18 (best 0.83) |
| 6BFZ | Crystal structure of enolase from E. COLI with a mixture of apo form, substrate, and product form | x-ray diffraction | A, B, E, F, D, C | MG, SO4, PEP, 2PG | 18 (best 0.83) |
| 6D3Q | Crystal structure of Escherichia coli enolase complexed with a natural inhibitor SF2312. | x-ray diffraction | A, C, B, E, F, D | 4NG, MG, SO4 | 18 (best 0.83) |
| 6D3Q | Crystal structure of escherichia COLI enolase complexed with a natural inhibitor SF2312. | x-ray diffraction | A, C, B, E, F, D | 4NG, MG, SO4 | 18 (best 0.83) |
| 6NPF | Structure of E.coli enolase in complex with an analog of the natural product SF-2312 metabolite. | x-ray diffraction | A, B, C, D, F, E | SO4, MG, KVM | 17 (best 0.83) |
| 6NPF | Structure of E.COLI enolase in complex with an analog of the natural product sf-2312 metabolite. | x-ray diffraction | A, B, C, D, F, E | SO4, MG, KVM | 17 (best 0.83) |
| B7MLA0 | AlphaFold monomer V2.0 prediction for enolase (B7MLA0) | predicted | A | — | — |
Ligands
- MG · Magnesium ion · in 8 records
- SO4 · Sulfate ion · in 8 records
- 2PG · 2-phosphoglyceric acid · in 4 records
- 4NG · [(3S,5S)-1,5-dihydroxy-2-oxopyrrolidin-3-yl]phosphonic acid · in 2 records
- KVM · [(3S)-1-hydroxy-2,5-dioxopyrrolidin-3-yl]phosphonic acid · in 2 records
- PEP · Phosphoenolpyruvate · in 2 records
Experiment against prediction
- 6BFZ chain E against the predicted model B7MLA0: TM-score 0.98, RMSD 0.43 Å
- 6BFZ chain E against the predicted model B7MLA0: TM-score 0.98, RMSD 0.43 Å
- 6BFY chain A against the predicted model B7MLA0: TM-score 0.98, RMSD 0.50 Å
- 6BFY chain A against the predicted model B7MLA0: TM-score 0.98, RMSD 0.50 Å
- 6BFY chain C against the predicted model B7MLA0: TM-score 0.98, RMSD 0.52 Å
- 6BFY chain C against the predicted model B7MLA0: TM-score 0.98, RMSD 0.52 Å
- 6D3Q chain E against the predicted model B7MLA0: TM-score 0.98, RMSD 0.57 Å
- 6D3Q chain E against the predicted model B7MLA0: TM-score 0.98, RMSD 0.57 Å
- 6D3Q chain F against the predicted model B7MLA0: TM-score 0.98, RMSD 0.58 Å
- 6D3Q chain F against the predicted model B7MLA0: TM-score 0.98, RMSD 0.58 Å
Elsewhere
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